Boolean modeling of mechanosensitive epithelial to mesenchymal transition and its reversal

Boolean modeling of mechanosensitive epithelial to mesenchymal transition and its reversal

Summary: The significance of biophysical modulators of the epithelial to mesenchymal transition (EMT) is demonstrated by experiments that document full EMT on stiff, nano-patterned substrates in the absence of biochemical induction. Yet, current models focus on biochemical triggers of EMT without ad...

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Bibliographic Details
Main Authors: Emmalee Sullivan, Marlayna Harris, Arnav Bhatnagar, Eric Guberman, Ian Zonfa, Erzsébet Ravasz Regan
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:iScience
Subjects:
Mechanobiology
Cell biology
Biophysics
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422300398X

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