Retrograde venous invasion in renal cell carcinoma: a gross diagnosis
Abstract Renal cell carcinoma, notably clear cell renal cell carcinoma in particular, show remarkable predisposition for intravenous growth. Retrograde venous invasion results in intravascular emboli in renal sinus and intrarenal veins, and nodules in renal parenchyma (after extravascular spread). I...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-02-01
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| Series: | Surgical and Experimental Pathology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42047-023-00127-z |
| _version_ | 1811166001630281728 |
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| author | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral |
| author_facet | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral |
| author_sort | Daniel Abensur Athanazio |
| collection | DOAJ |
| description | Abstract Renal cell carcinoma, notably clear cell renal cell carcinoma in particular, show remarkable predisposition for intravenous growth. Retrograde venous invasion results in intravascular emboli in renal sinus and intrarenal veins, and nodules in renal parenchyma (after extravascular spread). In our experience, we observed this phenomenon in five cases out of 204 renal cell tumors: four in clear cell renal cell carcinomas (4/166 or 2.4%) and 12.5% of those clear cell carcinomas with major renal vein invasion (4/34 or 12.5%). Since it is a recently described phenomenon, easily identifiable a bisected specimen, we believe it would be valuable to show our experience in recognizing and reporting the frequency of this finding in our practice. |
| first_indexed | 2024-04-10T15:45:18Z |
| format | Article |
| id | doaj.art-63cd751969ca456db51ec2d22bef6999 |
| institution | Directory Open Access Journal |
| issn | 2520-8454 |
| language | English |
| last_indexed | 2024-04-10T15:45:18Z |
| publishDate | 2023-02-01 |
| publisher | BMC |
| record_format | Article |
| series | Surgical and Experimental Pathology |
| spelling | doaj.art-63cd751969ca456db51ec2d22bef69992023-02-12T12:08:15ZengBMCSurgical and Experimental Pathology2520-84542023-02-01611510.1186/s42047-023-00127-zRetrograde venous invasion in renal cell carcinoma: a gross diagnosis Daniel Abensur Athanazio0Maiara Ferreira de Souza1Maria Estela Pompeu do Amaral2Imagepat, Laboratory of PathologyImagepat, Laboratory of PathologyImagepat, Laboratory of PathologyAbstract Renal cell carcinoma, notably clear cell renal cell carcinoma in particular, show remarkable predisposition for intravenous growth. Retrograde venous invasion results in intravascular emboli in renal sinus and intrarenal veins, and nodules in renal parenchyma (after extravascular spread). In our experience, we observed this phenomenon in five cases out of 204 renal cell tumors: four in clear cell renal cell carcinomas (4/166 or 2.4%) and 12.5% of those clear cell carcinomas with major renal vein invasion (4/34 or 12.5%). Since it is a recently described phenomenon, easily identifiable a bisected specimen, we believe it would be valuable to show our experience in recognizing and reporting the frequency of this finding in our practice.https://doi.org/10.1186/s42047-023-00127-zCarcinoma, cell carcinomaPathologyKidney NeoplasmsRenal veins |
| spellingShingle | Daniel Abensur Athanazio Maiara Ferreira de Souza Maria Estela Pompeu do Amaral Retrograde venous invasion in renal cell carcinoma: a gross diagnosis Surgical and Experimental Pathology Carcinoma, cell carcinoma Pathology Kidney Neoplasms Renal veins |
| title | Retrograde venous invasion in renal cell carcinoma: a gross diagnosis |
| title_full | Retrograde venous invasion in renal cell carcinoma: a gross diagnosis |
| title_fullStr | Retrograde venous invasion in renal cell carcinoma: a gross diagnosis |
| title_full_unstemmed | Retrograde venous invasion in renal cell carcinoma: a gross diagnosis |
| title_short | Retrograde venous invasion in renal cell carcinoma: a gross diagnosis |
| title_sort | retrograde venous invasion in renal cell carcinoma a gross diagnosis |
| topic | Carcinoma, cell carcinoma Pathology Kidney Neoplasms Renal veins |
| url | https://doi.org/10.1186/s42047-023-00127-z |
| work_keys_str_mv | AT danielabensurathanazio retrogradevenousinvasioninrenalcellcarcinomaagrossdiagnosis AT maiaraferreiradesouza retrogradevenousinvasioninrenalcellcarcinomaagrossdiagnosis AT mariaestelapompeudoamaral retrogradevenousinvasioninrenalcellcarcinomaagrossdiagnosis |