Immunoregulatory Roles of Osteopontin in Diseases
Osteopontin (OPN) is a multifunctional protein that plays a pivotal role in the immune system. It is involved in various biological processes, including cell adhesion, migration and survival. The study of the immunomodulatory effects of OPN is of paramount importance due to its potential therapeutic...
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| Format: | Article |
| Language: | English |
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MDPI AG
2024-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/16/2/312 |
| _version_ | 1797339478573973504 |
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| author | Lebei Wang Xiaoyin Niu |
| author_facet | Lebei Wang Xiaoyin Niu |
| author_sort | Lebei Wang |
| collection | DOAJ |
| description | Osteopontin (OPN) is a multifunctional protein that plays a pivotal role in the immune system. It is involved in various biological processes, including cell adhesion, migration and survival. The study of the immunomodulatory effects of OPN is of paramount importance due to its potential therapeutic applications. A comprehensive understanding of how OPN regulates the immune response could pave the way for the development of novel treatments for a multitude of diseases, including autoimmune disorders, infectious diseases and cancer. Therefore, in the following paper, we provide a systematic overview of OPN and its immunoregulatory roles in various diseases, laying the foundation for the development of OPN-based therapies in the future. |
| first_indexed | 2024-03-08T09:48:43Z |
| format | Article |
| id | doaj.art-63d32f01ba4341d1a986ca22d9388e4f |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-08T09:48:43Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-63d32f01ba4341d1a986ca22d9388e4f2024-01-29T14:10:24ZengMDPI AGNutrients2072-66432024-01-0116231210.3390/nu16020312Immunoregulatory Roles of Osteopontin in DiseasesLebei Wang0Xiaoyin Niu1Department of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaDepartment of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, ChinaOsteopontin (OPN) is a multifunctional protein that plays a pivotal role in the immune system. It is involved in various biological processes, including cell adhesion, migration and survival. The study of the immunomodulatory effects of OPN is of paramount importance due to its potential therapeutic applications. A comprehensive understanding of how OPN regulates the immune response could pave the way for the development of novel treatments for a multitude of diseases, including autoimmune disorders, infectious diseases and cancer. Therefore, in the following paper, we provide a systematic overview of OPN and its immunoregulatory roles in various diseases, laying the foundation for the development of OPN-based therapies in the future.https://www.mdpi.com/2072-6643/16/2/312osteopontinimmunoregulationdiseases |
| spellingShingle | Lebei Wang Xiaoyin Niu Immunoregulatory Roles of Osteopontin in Diseases Nutrients osteopontin immunoregulation diseases |
| title | Immunoregulatory Roles of Osteopontin in Diseases |
| title_full | Immunoregulatory Roles of Osteopontin in Diseases |
| title_fullStr | Immunoregulatory Roles of Osteopontin in Diseases |
| title_full_unstemmed | Immunoregulatory Roles of Osteopontin in Diseases |
| title_short | Immunoregulatory Roles of Osteopontin in Diseases |
| title_sort | immunoregulatory roles of osteopontin in diseases |
| topic | osteopontin immunoregulation diseases |
| url | https://www.mdpi.com/2072-6643/16/2/312 |
| work_keys_str_mv | AT lebeiwang immunoregulatoryrolesofosteopontinindiseases AT xiaoyinniu immunoregulatoryrolesofosteopontinindiseases |