Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044
Aims: Atrial fibrillation/atrial flutter (AF/AFL) is a critical public health issue worldwide, and its epidemiological patterns have changed over the decades. This work aimed to assess the global trends of AF/AFL and attributable risks from 1990 to 2019. Methods and results: The present study utiliz...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2024-01-01
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| Series: | Heliyon |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024000835 |
| _version_ | 1797328731310653440 |
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| author | Qunchao Ma Jinyun Zhu Pingping Zheng Jiaru Zhang Xiangyang Xia Yun Zhao Qingqiang Cheng Ning Zhang |
| author_facet | Qunchao Ma Jinyun Zhu Pingping Zheng Jiaru Zhang Xiangyang Xia Yun Zhao Qingqiang Cheng Ning Zhang |
| author_sort | Qunchao Ma |
| collection | DOAJ |
| description | Aims: Atrial fibrillation/atrial flutter (AF/AFL) is a critical public health issue worldwide, and its epidemiological patterns have changed over the decades. This work aimed to assess the global trends of AF/AFL and attributable risks from 1990 to 2019. Methods and results: The present study utilized data from the Global Burden of Disease Study 2019 to examine the temporal trends, attributable risks, and projections of AF/AFL. The estimated annual percentage change (EAPC) and age-standardized rate (ASR) were employed for this purpose. The findings revealed that in 2019, AF/AFL accounted for 4.72 million incident cases, 59.70 million prevalent cases, 0.32 million deaths, and 8.39 million disability-adjusted life years (DALYs). Furthermore, the results indicated that males under 70 years of age had a higher incidence, prevalence, and DALYs than females, while the rates were similar for both genders between 70 and 74 years. However, this pattern was reversed in individuals over the age of 75, with females exhibiting a higher total incidence, prevalence, and DALYs than males. The age-standardized rates (ASRs) of prevalence, incidence, mortality, and DALYs increased with an increase in the socio-demographic index (SDI). The three primary contributors to AF/AFL were high systolic blood pressure, high body-mass index, and smoking. Majority of risk factors exhibited a unimodal distribution, with a peak between the ages of 50 and 70. Conclusions: The disease burden of AF/AFL is still severe worldwide and getting worse. To encourage prevention and treatment, systematic regional surveillance of AF/AFL should be put in place. |
| first_indexed | 2024-03-08T06:55:54Z |
| format | Article |
| id | doaj.art-63dc7ff7279b4e0eac95649222b960f5 |
| institution | Directory Open Access Journal |
| issn | 2405-8440 |
| language | English |
| last_indexed | 2024-03-08T06:55:54Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Heliyon |
| spelling | doaj.art-63dc7ff7279b4e0eac95649222b960f52024-02-03T06:36:07ZengElsevierHeliyon2405-84402024-01-01102e24052Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044Qunchao Ma0Jinyun Zhu1Pingping Zheng2Jiaru Zhang3Xiangyang Xia4Yun Zhao5Qingqiang Cheng6Ning Zhang7Department of Cardiology, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR ChinaDepartment of Cardiology, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR ChinaDepartment of Emergency, The Affiliated Hangzhou First People's Hospital, College of Medicine, Westlake University, Hangzhou, Zhejiang Province, 310006, PR ChinaDepartment of Cardiology, the First Affiliated Hospital of Fujian Medical University, Fuzhou, Fujian Province, 350000, PR ChinaDepartment of Cardiology, Second Affiliated Hospital, Zhejiang University College of Medicine, 88 Jiefang Rd, Hangzhou, Zhejiang Province, 310009, PR ChinaDepartment of Ultrasound, Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong Province, 271000, PR ChinaDepartment of Cardiology, the Affiliated Hangzhou First People’s Hospital, College of Medicine, Westlake University, Hangzhou, Zhejiang Province, 310006, PR ChinaDepartment of Cardiology, the Affiliated Hangzhou First People’s Hospital, College of Medicine, Westlake University, Hangzhou, Zhejiang Province, 310006, PR China; Corresponding author.Aims: Atrial fibrillation/atrial flutter (AF/AFL) is a critical public health issue worldwide, and its epidemiological patterns have changed over the decades. This work aimed to assess the global trends of AF/AFL and attributable risks from 1990 to 2019. Methods and results: The present study utilized data from the Global Burden of Disease Study 2019 to examine the temporal trends, attributable risks, and projections of AF/AFL. The estimated annual percentage change (EAPC) and age-standardized rate (ASR) were employed for this purpose. The findings revealed that in 2019, AF/AFL accounted for 4.72 million incident cases, 59.70 million prevalent cases, 0.32 million deaths, and 8.39 million disability-adjusted life years (DALYs). Furthermore, the results indicated that males under 70 years of age had a higher incidence, prevalence, and DALYs than females, while the rates were similar for both genders between 70 and 74 years. However, this pattern was reversed in individuals over the age of 75, with females exhibiting a higher total incidence, prevalence, and DALYs than males. The age-standardized rates (ASRs) of prevalence, incidence, mortality, and DALYs increased with an increase in the socio-demographic index (SDI). The three primary contributors to AF/AFL were high systolic blood pressure, high body-mass index, and smoking. Majority of risk factors exhibited a unimodal distribution, with a peak between the ages of 50 and 70. Conclusions: The disease burden of AF/AFL is still severe worldwide and getting worse. To encourage prevention and treatment, systematic regional surveillance of AF/AFL should be put in place.http://www.sciencedirect.com/science/article/pii/S2405844024000835Atrial fibrillation/atrial flutterDisease burdenEstimated annual percentage changeAge-standardized rateRisk factorsPrediction |
| spellingShingle | Qunchao Ma Jinyun Zhu Pingping Zheng Jiaru Zhang Xiangyang Xia Yun Zhao Qingqiang Cheng Ning Zhang Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 Heliyon Atrial fibrillation/atrial flutter Disease burden Estimated annual percentage change Age-standardized rate Risk factors Prediction |
| title | Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 |
| title_full | Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 |
| title_fullStr | Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 |
| title_full_unstemmed | Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 |
| title_short | Global burden of atrial fibrillation/flutter: Trends from 1990 to 2019 and projections until 2044 |
| title_sort | global burden of atrial fibrillation flutter trends from 1990 to 2019 and projections until 2044 |
| topic | Atrial fibrillation/atrial flutter Disease burden Estimated annual percentage change Age-standardized rate Risk factors Prediction |
| url | http://www.sciencedirect.com/science/article/pii/S2405844024000835 |
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