Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass

Bleeding is a common problem during resection of a retroperitoneal mass. Massive bleeding may occur in case of injury of an adjacent major vessel or organ. This case report describes a successful anesthetic management of a patient with 10 l of blood loss within three hours surgery. A 44-year-old wom...

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Main Authors: Xueqin Zhu, Yu Gui, Binbin Zhu, Jian Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2015-04-01
Series:Egyptian Journal of Anaesthesia
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110184915000057
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author Xueqin Zhu
Yu Gui
Binbin Zhu
Jian Sun
author_facet Xueqin Zhu
Yu Gui
Binbin Zhu
Jian Sun
author_sort Xueqin Zhu
collection DOAJ
description Bleeding is a common problem during resection of a retroperitoneal mass. Massive bleeding may occur in case of injury of an adjacent major vessel or organ. This case report describes a successful anesthetic management of a patient with 10 l of blood loss within three hours surgery. A 44-year-old woman who underwent an operation for resection of a retroperitoneal mass, went to a hypovolemic shock, due to acute life-threatening intra-operative bleeding, and was successfully rescued with a combination of measures, including control of surgical bleeding, supportive treatment with rapid fluid infusion, massive transfusion of blood products and administration of intravenous vasoactive agents for maintaining tissue perfusion and oxygenation, utilizing intraoperative autologous blood salvaged via cell saver, as well as prevention and treatment of complications. The patient received a total of 22 units of Packet Red Blood Cells (PRBCs), 18 units of Fresh Frozen Plasma (FFP), 10 units of cryoprecipitate, 3750 ml of her own salvage blood. Postoperatively, she was transferred to the intensive care unit (ICU) with mechanical ventilator support, where she received another 5.4 units of FFP, 10 units of cryoprecipitate. The patient developed features of early acute lung injury such as fever and hypoxemia, and was managed successfully with mechanical ventilator support for a few days. At a three-month follow-up, the patient was doing very well. This paper explores the pathogenesia, implications, prevention and treatment of the transfusion-associated complications such as acidosis, hypothermia, electrolyte abnormalities, and transfusion-related acute lung injury (TRALI). Particular attention is given to the prevention of secondary coagulopathy of the patient requiring massive blood transfusion. This case study presents a good reference for similar anesthetic scenario in the future.
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spelling doaj.art-63dd47b105554e4395d6659c7d088b2f2022-12-21T19:37:35ZengTaylor & Francis GroupEgyptian Journal of Anaesthesia1110-18492015-04-0131220721310.1016/j.egja.2015.01.003Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal massXueqin ZhuYu GuiBinbin ZhuJian SunBleeding is a common problem during resection of a retroperitoneal mass. Massive bleeding may occur in case of injury of an adjacent major vessel or organ. This case report describes a successful anesthetic management of a patient with 10 l of blood loss within three hours surgery. A 44-year-old woman who underwent an operation for resection of a retroperitoneal mass, went to a hypovolemic shock, due to acute life-threatening intra-operative bleeding, and was successfully rescued with a combination of measures, including control of surgical bleeding, supportive treatment with rapid fluid infusion, massive transfusion of blood products and administration of intravenous vasoactive agents for maintaining tissue perfusion and oxygenation, utilizing intraoperative autologous blood salvaged via cell saver, as well as prevention and treatment of complications. The patient received a total of 22 units of Packet Red Blood Cells (PRBCs), 18 units of Fresh Frozen Plasma (FFP), 10 units of cryoprecipitate, 3750 ml of her own salvage blood. Postoperatively, she was transferred to the intensive care unit (ICU) with mechanical ventilator support, where she received another 5.4 units of FFP, 10 units of cryoprecipitate. The patient developed features of early acute lung injury such as fever and hypoxemia, and was managed successfully with mechanical ventilator support for a few days. At a three-month follow-up, the patient was doing very well. This paper explores the pathogenesia, implications, prevention and treatment of the transfusion-associated complications such as acidosis, hypothermia, electrolyte abnormalities, and transfusion-related acute lung injury (TRALI). Particular attention is given to the prevention of secondary coagulopathy of the patient requiring massive blood transfusion. This case study presents a good reference for similar anesthetic scenario in the future.http://www.sciencedirect.com/science/article/pii/S1110184915000057Massive transfusionCoagulopathyHypokalemiaRetroperitoneal mass
spellingShingle Xueqin Zhu
Yu Gui
Binbin Zhu
Jian Sun
Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
Egyptian Journal of Anaesthesia
Massive transfusion
Coagulopathy
Hypokalemia
Retroperitoneal mass
title Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
title_full Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
title_fullStr Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
title_full_unstemmed Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
title_short Anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
title_sort anesthetic management of a patient with 10 l of blood loss during operation for a retroperitoneal mass
topic Massive transfusion
Coagulopathy
Hypokalemia
Retroperitoneal mass
url http://www.sciencedirect.com/science/article/pii/S1110184915000057
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AT binbinzhu anestheticmanagementofapatientwith10lofbloodlossduringoperationforaretroperitonealmass
AT jiansun anestheticmanagementofapatientwith10lofbloodlossduringoperationforaretroperitonealmass