Incidental Gallbladder Carcinoma: An Eastern Indian Experience and Necessity of Routine Histopathological Examination after All Cholecystectomy
Introduction: The carcinoma of gallbladder is the most common malignancy of the biliary tract. The incidence of this carcinoma varies geographically. Incidental gallbladder carcinoma is diagnosed during histopathological examination after cholecystectomy due to other reasons. Histopathological...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
JCDR Research and Publications Pvt. Ltd.
2022-10-01
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Series: | National Journal of Laboratory Medicine |
Subjects: | |
Online Access: | https://www.njlm.net/articles/PDF/2661/55484_CE[Nik]_F(SHU)_PF1(AG_SHU)_PN(SHU).pdf |
Summary: | Introduction: The carcinoma of gallbladder is the most
common malignancy of the biliary tract. The incidence of
this carcinoma varies geographically. Incidental gallbladder
carcinoma is diagnosed during histopathological examination
after cholecystectomy due to other reasons. Histopathological
examination of all cholecystectomy specimens are very essential
to rule out these incidental gallbladder carcinomas.
Aim: To this study to estimate the frequency of incidental
gallbladder carcinoma in patients undergoing routine
cholecystectomy and also to evaluate the necessity of routine
histopathological examination after all cholecystectomy.
Materials and Methods: A retrospective observational study
was conducted in Department of Pathology, Midnapore Medical
College and Hospital, West Bengal, India between January
2014 to December 2019 (six years) covering 650 patients
who underwent laparoscopic and open cholecystectomy.
Patients' demographic data, pathologic results, macroscopic
appearance of the specimen, cancer staging were recorded
and frequency of incidental gallbladder carcinoma were
calculated.
Result: Total 650 cholecystectomy specimens due to benign
gallbladder disease were received in pathology department.
Histopathological examination revealed 18 cases of incidental
gallbladder carcinoma which comprised 2.8% of all the
cholecystectomies. Among them 13 were female and five were
in male with male: female ratio of 1:2.6 and the age ranges from
35 to 68 years. Among 18 cases 10 cases showed invasion upto
lamina propria (stage T1a), five) cases had invasion in muscular
layer (stage T1b) and three cases showed perimuscular
connective tissue invasion (stage T2a).
Conclution: The present study observed that the incidence of
incidental gallbladder carcinoma in cholecystectomy specimen
was little higher range in East Indian population and so routine
histopathological examination of all cholecystectomy specimens
are recommended |
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ISSN: | 2277-8551 2455-6882 |