Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure
Elzbieta Skorupska,1 Marta Jokiel,1,2 Michał Rychlik,3 Rafał Łochowski,4 Małgorzata Kotwicka5 1Department of Physiotherapy, Poznan University of Medical Sciences, Poznan, Poland; 2Department of Orthopedics, Traumatology and Hand Surgery Poznan University of Medical Sciences, Poznan, Poland; 3Departm...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2020-12-01
|
| Series: | Journal of Pain Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/female-overrepresentation-in-low-back-related-leg-pain-a-retrospective-peer-reviewed-article-JPR |
| _version_ | 1818385489505288192 |
|---|---|
| author | Skorupska E Jokiel M Rychlik M Łochowski R Kotwicka M |
| author_facet | Skorupska E Jokiel M Rychlik M Łochowski R Kotwicka M |
| author_sort | Skorupska E |
| collection | DOAJ |
| description | Elzbieta Skorupska,1 Marta Jokiel,1,2 Michał Rychlik,3 Rafał Łochowski,4 Małgorzata Kotwicka5 1Department of Physiotherapy, Poznan University of Medical Sciences, Poznan, Poland; 2Department of Orthopedics, Traumatology and Hand Surgery Poznan University of Medical Sciences, Poznan, Poland; 3Department of Virtual Engineering, Poznan University of Technology, Poznan, Poland; 4Department of Mathematics and Mathematical Economics, Warsaw School of Economics, Warsaw, Poland; 5Department of Cell Biology, Poznan University of Medical Sciences, Poznan, PolandCorrespondence: Elzbieta SkorupskaDepartment of Physiotherapy, Poznan University of Medical Sciences, Smoluchowskiego 11, Poznan 60-179, PolandTel/Fax +48 61 831-02-17Email skorupska@ump.edu.plBackground: The newly proposed low back pain treatment requires case classification according to the pain mechanism (nociceptive, neuropathic or nociplastic) to determine the most effective therapeutic approach. However, there is a lack of objective tools for distinguishing these pain mechanisms. The aim of the study was to identify which symptoms, signs, and standard diagnostic parameters would allow predicting the nociplastic pain (NP) subtype among low back leg pain (LBLP) patients.Methods: A retrospective analysis of an LBLP case–control study database was carried out. The presence of NP was assumed if the patient presented with myofascial pain syndrome (MPS) and developed a short-term intensive vasodilatation reaction in the perceived lower leg pain area after provocation by a minimally invasive procedure. Clinical data and standard LBLP diagnostic parameters were analyzed to classify patients as NP (+) vs NP (-). Next, to predict NP probability, logistic regression analysis and a diagnostic classification tree were constructed.Results: NP was confirmed in 43.75% of LBLP patients. Women represented 95.24% of all NP (+) patients. The diagnostic classification tree indicated that NP was highly probable if the LBLP subject was female and the result of a positive straight leg raise (SLR) test was lower than 45 degrees. If the SLR test result was greater than or equal to 45 degrees, a negative result on the Bragard test would have diagnostic value. This classification tree was approved to a certain extent in the logistic regression model (deviance residuals, min: − 1.8519; 1Q: − 0.5551; median: − 0.1907; 3Q: 0.6565 and max: 2.1058) but should be verified in a larger group of subjects.Conclusion: Female sex, but not clinical data or standard diagnostic parameters, is indicative of nociplastic pain in LBLP patients. More sophisticated statistical methods, based on directly measurable parameters, should be proposed to distinguish NP involvement in LBLP.Keywords: central sensitization, low back pain, nociplastic pain, myofascial pain syndrome, thermovision |
| first_indexed | 2024-12-14T03:38:58Z |
| format | Article |
| id | doaj.art-63e622a169214792956033a65bda4a8d |
| institution | Directory Open Access Journal |
| issn | 1178-7090 |
| language | English |
| last_indexed | 2024-12-14T03:38:58Z |
| publishDate | 2020-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Pain Research |
| spelling | doaj.art-63e622a169214792956033a65bda4a8d2022-12-21T23:18:32ZengDove Medical PressJournal of Pain Research1178-70902020-12-01Volume 133427343560507Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive ProcedureSkorupska EJokiel MRychlik MŁochowski RKotwicka MElzbieta Skorupska,1 Marta Jokiel,1,2 Michał Rychlik,3 Rafał Łochowski,4 Małgorzata Kotwicka5 1Department of Physiotherapy, Poznan University of Medical Sciences, Poznan, Poland; 2Department of Orthopedics, Traumatology and Hand Surgery Poznan University of Medical Sciences, Poznan, Poland; 3Department of Virtual Engineering, Poznan University of Technology, Poznan, Poland; 4Department of Mathematics and Mathematical Economics, Warsaw School of Economics, Warsaw, Poland; 5Department of Cell Biology, Poznan University of Medical Sciences, Poznan, PolandCorrespondence: Elzbieta SkorupskaDepartment of Physiotherapy, Poznan University of Medical Sciences, Smoluchowskiego 11, Poznan 60-179, PolandTel/Fax +48 61 831-02-17Email skorupska@ump.edu.plBackground: The newly proposed low back pain treatment requires case classification according to the pain mechanism (nociceptive, neuropathic or nociplastic) to determine the most effective therapeutic approach. However, there is a lack of objective tools for distinguishing these pain mechanisms. The aim of the study was to identify which symptoms, signs, and standard diagnostic parameters would allow predicting the nociplastic pain (NP) subtype among low back leg pain (LBLP) patients.Methods: A retrospective analysis of an LBLP case–control study database was carried out. The presence of NP was assumed if the patient presented with myofascial pain syndrome (MPS) and developed a short-term intensive vasodilatation reaction in the perceived lower leg pain area after provocation by a minimally invasive procedure. Clinical data and standard LBLP diagnostic parameters were analyzed to classify patients as NP (+) vs NP (-). Next, to predict NP probability, logistic regression analysis and a diagnostic classification tree were constructed.Results: NP was confirmed in 43.75% of LBLP patients. Women represented 95.24% of all NP (+) patients. The diagnostic classification tree indicated that NP was highly probable if the LBLP subject was female and the result of a positive straight leg raise (SLR) test was lower than 45 degrees. If the SLR test result was greater than or equal to 45 degrees, a negative result on the Bragard test would have diagnostic value. This classification tree was approved to a certain extent in the logistic regression model (deviance residuals, min: − 1.8519; 1Q: − 0.5551; median: − 0.1907; 3Q: 0.6565 and max: 2.1058) but should be verified in a larger group of subjects.Conclusion: Female sex, but not clinical data or standard diagnostic parameters, is indicative of nociplastic pain in LBLP patients. More sophisticated statistical methods, based on directly measurable parameters, should be proposed to distinguish NP involvement in LBLP.Keywords: central sensitization, low back pain, nociplastic pain, myofascial pain syndrome, thermovisionhttps://www.dovepress.com/female-overrepresentation-in-low-back-related-leg-pain-a-retrospective-peer-reviewed-article-JPRcentral sensitizationlow back painnociplastic painmyofascial pain syndromethermovision |
| spellingShingle | Skorupska E Jokiel M Rychlik M Łochowski R Kotwicka M Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure Journal of Pain Research central sensitization low back pain nociplastic pain myofascial pain syndrome thermovision |
| title | Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure |
| title_full | Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure |
| title_fullStr | Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure |
| title_full_unstemmed | Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure |
| title_short | Female Overrepresentation in Low Back-Related Leg Pain: A Retrospective Study of the Autonomic Response to a Minimally Invasive Procedure |
| title_sort | female overrepresentation in low back related leg pain a retrospective study of the autonomic response to a minimally invasive procedure |
| topic | central sensitization low back pain nociplastic pain myofascial pain syndrome thermovision |
| url | https://www.dovepress.com/female-overrepresentation-in-low-back-related-leg-pain-a-retrospective-peer-reviewed-article-JPR |
| work_keys_str_mv | AT skorupskae femaleoverrepresentationinlowbackrelatedlegpainaretrospectivestudyoftheautonomicresponsetoaminimallyinvasiveprocedure AT jokielm femaleoverrepresentationinlowbackrelatedlegpainaretrospectivestudyoftheautonomicresponsetoaminimallyinvasiveprocedure AT rychlikm femaleoverrepresentationinlowbackrelatedlegpainaretrospectivestudyoftheautonomicresponsetoaminimallyinvasiveprocedure AT łochowskir femaleoverrepresentationinlowbackrelatedlegpainaretrospectivestudyoftheautonomicresponsetoaminimallyinvasiveprocedure AT kotwickam femaleoverrepresentationinlowbackrelatedlegpainaretrospectivestudyoftheautonomicresponsetoaminimallyinvasiveprocedure |