Robustness evaluations of pathway activity inference methods on gene expression data

Robustness evaluations of pathway activity inference methods on gene expression data

Abstract Background With the exponential growth of high-throughput technologies, multiple pathway analysis methods have been proposed to estimate pathway activities from gene expression profiles. These pathway activity inference methods can be divided into two main categories: non-Topology-Based (no...

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Bibliographic Details
Main Authors: Tay Xin Hui, Shahreen Kasim, Izzatdin Abdul Aziz, Mohd Farhan Md Fudzee, Nazleeni Samiha Haron, Tole Sutikno, Rohayanti Hassan, Hairulnizam Mahdin, Seah Choon Sen
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Bioinformatics
Subjects:
Pathway analysis
Reproducibility power
Robustness
PubMed text data mining
Literature validation
Pathway activity inference
Online Access:https://doi.org/10.1186/s12859-024-05632-w

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