Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023
Because epidemiologic and environmental risk factors for nontuberculous mycobacteria (NTM) have been reported only infrequently, little information exists about those factors. The state of Virginia, USA, requires certain ecologic features to be included in reports to the Virginia Department of Heal...
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| Format: | Article |
| Language: | English |
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Centers for Disease Control and Prevention
2024-03-01
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| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/30/3/23-1162_article |
| _version_ | 1797299296212615168 |
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| author | Brendan Mullen Eric R. Houpt Josh Colston Lea Becker Sharon Johnson Laura Young Jasie Hearn Joe Falkinham Scott K. Heysell |
| author_facet | Brendan Mullen Eric R. Houpt Josh Colston Lea Becker Sharon Johnson Laura Young Jasie Hearn Joe Falkinham Scott K. Heysell |
| author_sort | Brendan Mullen |
| collection | DOAJ |
| description |
Because epidemiologic and environmental risk factors for nontuberculous mycobacteria (NTM) have been reported only infrequently, little information exists about those factors. The state of Virginia, USA, requires certain ecologic features to be included in reports to the Virginia Department of Health, presenting a unique opportunity to study those variables. We analyzed laboratory reports of Mycobacterium avium complex (MAC) and M. abscessus infections in Virginia during 2021–2023. MAC/M. abscessus was isolated from 6.19/100,000 persons, and 2.37/100,000 persons had MAC/M. abscessus lung disease. M. abscessus accounted for 17.4% and MAC for 82.6% of cases. Saturated vapor pressure was associated with MAC/M. abscessus prevalence (prevalence ratio 1.414, 95% CI 1.011–1.980; p = 0.043). Self-supplied water use was a protective factor (incidence rate ratio 0.304, 95% CI 0.098–0.950; p = 0.041). Our findings suggest that a better understanding of geographic clustering and environmental water exposures could help develop future targeted prevention and control efforts.
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| first_indexed | 2024-03-07T22:48:32Z |
| format | Article |
| id | doaj.art-63e8b006b226462ca3e0e02b3d23a2b6 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-03-07T22:48:32Z |
| publishDate | 2024-03-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-63e8b006b226462ca3e0e02b3d23a2b62024-02-23T14:01:39ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592024-03-0130354855410.3201/eid3003.231162Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023Brendan MullenEric R. HouptJosh ColstonLea BeckerSharon JohnsonLaura YoungJasie HearnJoe FalkinhamScott K. Heysell Because epidemiologic and environmental risk factors for nontuberculous mycobacteria (NTM) have been reported only infrequently, little information exists about those factors. The state of Virginia, USA, requires certain ecologic features to be included in reports to the Virginia Department of Health, presenting a unique opportunity to study those variables. We analyzed laboratory reports of Mycobacterium avium complex (MAC) and M. abscessus infections in Virginia during 2021–2023. MAC/M. abscessus was isolated from 6.19/100,000 persons, and 2.37/100,000 persons had MAC/M. abscessus lung disease. M. abscessus accounted for 17.4% and MAC for 82.6% of cases. Saturated vapor pressure was associated with MAC/M. abscessus prevalence (prevalence ratio 1.414, 95% CI 1.011–1.980; p = 0.043). Self-supplied water use was a protective factor (incidence rate ratio 0.304, 95% CI 0.098–0.950; p = 0.041). Our findings suggest that a better understanding of geographic clustering and environmental water exposures could help develop future targeted prevention and control efforts. https://wwwnc.cdc.gov/eid/article/30/3/23-1162_articlenontuberculous mycobacteriaMycobacterium abscessusMycobacterium avium complexrespiratory infectionstuberculosis and other mycobacteriaepidemiology |
| spellingShingle | Brendan Mullen Eric R. Houpt Josh Colston Lea Becker Sharon Johnson Laura Young Jasie Hearn Joe Falkinham Scott K. Heysell Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 Emerging Infectious Diseases nontuberculous mycobacteria Mycobacterium abscessus Mycobacterium avium complex respiratory infections tuberculosis and other mycobacteria epidemiology |
| title | Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 |
| title_full | Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 |
| title_fullStr | Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 |
| title_full_unstemmed | Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 |
| title_short | Geographic Variation and Environmental Predictors of Nontuberculous Mycobacteria in Laboratory Surveillance, Virginia, USA, 2021–2023 |
| title_sort | geographic variation and environmental predictors of nontuberculous mycobacteria in laboratory surveillance virginia usa 2021 2023 |
| topic | nontuberculous mycobacteria Mycobacterium abscessus Mycobacterium avium complex respiratory infections tuberculosis and other mycobacteria epidemiology |
| url | https://wwwnc.cdc.gov/eid/article/30/3/23-1162_article |
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