Search for new photosensitizers in photodynamic therapy

The review of photosensityzers for photodynamic therapy and fluorescent diagnosis, which are being developed, investigated and applied in clinical practice in Russia and other countries, is represented. Principal properties of photosensitizers based on derivatives of hematoporfirin, chlorines, phtal...

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Main Author: E. A. Lukiyanets
Format: Article
Language:Russian
Published: Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" 2013-09-01
Series:Biomedical Photonics
Subjects:
Online Access:https://www.pdt-journal.com/jour/article/view/15
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author E. A. Lukiyanets
author_facet E. A. Lukiyanets
author_sort E. A. Lukiyanets
collection DOAJ
description The review of photosensityzers for photodynamic therapy and fluorescent diagnosis, which are being developed, investigated and applied in clinical practice in Russia and other countries, is represented. Principal properties of photosensitizers based on derivatives of hematoporfirin, chlorines, phtalocyanines, naphthalocyanines, benzoporphyrins, pheophorbides, porphycenes etc are described. Main drugs based on these agents are listed, the field of clinical application is indicated. Special consideration is given to phtalocyanines derivatives and its structural analogues. In particular Russian photosensitizers developed in Research Institute of Organic Intermediates and Dyes under the Program for development and health care practical assimilation of new methods and means of prevention, diagnosis and treatment of cancer, infection and other hazardous diseases are traversed in the article. Methods of synthesis are described, spectral, physical and biological characteristics of synthesized compounds are shown.
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spelling doaj.art-63ea750026a041589d824a6a51aa56ff2023-03-13T07:12:29ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322013-09-012331615Search for new photosensitizers in photodynamic therapyE. A. Lukiyanets0Научно-исследовательский институт органических полупродуктов и красителей, Москва, РоссияThe review of photosensityzers for photodynamic therapy and fluorescent diagnosis, which are being developed, investigated and applied in clinical practice in Russia and other countries, is represented. Principal properties of photosensitizers based on derivatives of hematoporfirin, chlorines, phtalocyanines, naphthalocyanines, benzoporphyrins, pheophorbides, porphycenes etc are described. Main drugs based on these agents are listed, the field of clinical application is indicated. Special consideration is given to phtalocyanines derivatives and its structural analogues. In particular Russian photosensitizers developed in Research Institute of Organic Intermediates and Dyes under the Program for development and health care practical assimilation of new methods and means of prevention, diagnosis and treatment of cancer, infection and other hazardous diseases are traversed in the article. Methods of synthesis are described, spectral, physical and biological characteristics of synthesized compounds are shown.https://www.pdt-journal.com/jour/article/view/15фотосенсибилизаторыфотодинамическая терапияфталоцианины
spellingShingle E. A. Lukiyanets
Search for new photosensitizers in photodynamic therapy
Biomedical Photonics
фотосенсибилизаторы
фотодинамическая терапия
фталоцианины
title Search for new photosensitizers in photodynamic therapy
title_full Search for new photosensitizers in photodynamic therapy
title_fullStr Search for new photosensitizers in photodynamic therapy
title_full_unstemmed Search for new photosensitizers in photodynamic therapy
title_short Search for new photosensitizers in photodynamic therapy
title_sort search for new photosensitizers in photodynamic therapy
topic фотосенсибилизаторы
фотодинамическая терапия
фталоцианины
url https://www.pdt-journal.com/jour/article/view/15
work_keys_str_mv AT ealukiyanets searchfornewphotosensitizersinphotodynamictherapy