2-Methyl-4-Oxo-4,5-Dihydro-1<i>H</i>-Pyrrole-3-Carboxylic Acid Phenylamide

2-Methyl-4-oxo-4,5-dihydro-1<i>H</i>-pyrrole-3-carboxylic acid phenylamide was obtained as a single product in an experiment on the cyclization modes of a glycine-derived enamino amide. High yield and operational simplicity are the main features of the presented synthetic procedure. Addi...

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Bibliographic Details
Main Authors: Plamen Angelov, Pavel Yanev
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Molbank
Subjects:
Online Access:https://www.mdpi.com/1422-8599/2024/1/M1778
Description
Summary:2-Methyl-4-oxo-4,5-dihydro-1<i>H</i>-pyrrole-3-carboxylic acid phenylamide was obtained as a single product in an experiment on the cyclization modes of a glycine-derived enamino amide. High yield and operational simplicity are the main features of the presented synthetic procedure. Additionally, this result extends our previous observations on the cyclization reactions of similarly functionalized enamines, by revealing the preferred cyclization pathway under Boc-deprotection conditions.
ISSN:1422-8599