Ndr2 Kinase Controls Neurite Outgrowth and Dendritic Branching Through α1 Integrin Expression

Ndr2 Kinase Controls Neurite Outgrowth and Dendritic Branching Through α1 Integrin Expression

The serine/threonine kinase Ndr2 has been shown to control the inside-out activation of the β1subunit of integrins and the formation of neurites in both primary neurons and neurally differentiated pheochromacytoma (PC12) cells. In this study, we demonstrate that Ndr2 kinase furthermore determines th...

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Bibliographic Details
Main Authors: Yunus E. Demiray, Kati Rehberg, Stefanie Kliche, Oliver Stork
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Ndr kinase
integrin inside-out signaling
α1 integrin
neurite outgrowth
dendritic branching
pheochromocytoma
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2018.00066/full

Internet

http://journal.frontiersin.org/article/10.3389/fnmol.2018.00066/full

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