Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population
Background: Hypertension is a leading problem; it affects around thirty million adult Egyptians, according to the last national registry. The exact prevalence of resistant hypertension (RH) in Egypt wasn’t spotted before. The purpose of this study was to determine the prevalence, predictors, and imp...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Ubiquity Press
2023-06-01
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| Series: | Global Heart |
| Subjects: | |
| Online Access: | https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1211 |
| _version_ | 1797777790238457856 |
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| author | Mohamed Khalfallah Ayman Elsheikh Ahmad Eissa Basma Elnagar |
| author_facet | Mohamed Khalfallah Ayman Elsheikh Ahmad Eissa Basma Elnagar |
| author_sort | Mohamed Khalfallah |
| collection | DOAJ |
| description | Background: Hypertension is a leading problem; it affects around thirty million adult Egyptians, according to the last national registry. The exact prevalence of resistant hypertension (RH) in Egypt wasn’t spotted before. The purpose of this study was to determine the prevalence, predictors, and impact on adverse cardiovascular outcomes among adult Egyptians with RH. Methods: The present study examined a cohort of 990 hypertensive patients who were divided into two groups based on their blood pressure control; group I (n = 842) patients who achieved blood pressure control and group II (n = 148) patients who met the RH definition criteria. All patients underwent a close follow-up for one year to evaluate the major cardiovascular events. Results: The prevalence of RH was 14.9%. The main predictors impacting the cardiovascular outcomes of RH were advanced age (≥65 years), the presence of chronic kidney diseases, a BMI ≥ 30 kg/m2, and NSAID use. After one year of follow-up, the RH group displayed noticeably higher rates of major cardiovascular events, including new-onset atrial fibrillation (6.8% vs. 2.5%, P = 0.006), cerebral stroke (4.1% vs. 1.2%, P = 0.011), myocardial infarction (4.7% vs. 1.3%, P = 0.004), and acute heart failure (4.7% vs. 1.8%, P = 0.025). Conclusion: The prevalence of RH in Egypt is moderately high. Patients with RH have a far higher risk of cardiovascular events than those whose blood pressure is within control. |
| first_indexed | 2024-03-12T23:09:36Z |
| format | Article |
| id | doaj.art-63fa873e7279469f9177465ff05aa745 |
| institution | Directory Open Access Journal |
| issn | 2211-8179 |
| language | English |
| last_indexed | 2024-03-12T23:09:36Z |
| publishDate | 2023-06-01 |
| publisher | Ubiquity Press |
| record_format | Article |
| series | Global Heart |
| spelling | doaj.art-63fa873e7279469f9177465ff05aa7452023-07-18T08:15:39ZengUbiquity PressGlobal Heart2211-81792023-06-01181313110.5334/gh.12111192Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian PopulationMohamed Khalfallah0https://orcid.org/0000-0002-6105-9300Ayman Elsheikh1https://orcid.org/0000-0001-6956-2034Ahmad Eissa2https://orcid.org/0000-0001-9174-9495Basma Elnagar3https://orcid.org/0000-0002-5569-5781Assistant professor of cardiovascular medicine, cardiovascular department, faculty of Medicine, Tanta UniversityAssistant professor of cardiovascular medicine, cardiovascular department, faculty of Medicine, Tanta UniversityLecturer of endocrinology, internal medicine department, faculty of Medicine, Tanta UniversityLecturer of cardiovascular medicine, cardiovascular department, faculty of Medicine, Tanta UniversityBackground: Hypertension is a leading problem; it affects around thirty million adult Egyptians, according to the last national registry. The exact prevalence of resistant hypertension (RH) in Egypt wasn’t spotted before. The purpose of this study was to determine the prevalence, predictors, and impact on adverse cardiovascular outcomes among adult Egyptians with RH. Methods: The present study examined a cohort of 990 hypertensive patients who were divided into two groups based on their blood pressure control; group I (n = 842) patients who achieved blood pressure control and group II (n = 148) patients who met the RH definition criteria. All patients underwent a close follow-up for one year to evaluate the major cardiovascular events. Results: The prevalence of RH was 14.9%. The main predictors impacting the cardiovascular outcomes of RH were advanced age (≥65 years), the presence of chronic kidney diseases, a BMI ≥ 30 kg/m2, and NSAID use. After one year of follow-up, the RH group displayed noticeably higher rates of major cardiovascular events, including new-onset atrial fibrillation (6.8% vs. 2.5%, P = 0.006), cerebral stroke (4.1% vs. 1.2%, P = 0.011), myocardial infarction (4.7% vs. 1.3%, P = 0.004), and acute heart failure (4.7% vs. 1.8%, P = 0.025). Conclusion: The prevalence of RH in Egypt is moderately high. Patients with RH have a far higher risk of cardiovascular events than those whose blood pressure is within control.https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1211prevalencepredictorsoutcomesresistant hypertensionegyptian population |
| spellingShingle | Mohamed Khalfallah Ayman Elsheikh Ahmad Eissa Basma Elnagar Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population Global Heart prevalence predictors outcomes resistant hypertension egyptian population |
| title | Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population |
| title_full | Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population |
| title_fullStr | Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population |
| title_full_unstemmed | Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population |
| title_short | Prevalence, Predictors, and Outcomes of Resistant Hypertension in Egyptian Population |
| title_sort | prevalence predictors and outcomes of resistant hypertension in egyptian population |
| topic | prevalence predictors outcomes resistant hypertension egyptian population |
| url | https://account.globalheartjournal.com/index.php/up-j-gh/article/view/1211 |
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