Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children
Background: Arrhythmia is the most common complication after transcatheter closure of a ventricular septal defect (VSD). However, the effects of postprocedural left anterior fascicular block are not clear. This study presents the clinical characteristics, prognosis, and related risk factors of left...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2021-06-01
|
| Series: | Frontiers in Cardiovascular Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2021.609531/full |
| _version_ | 1818668390888243200 |
|---|---|
| author | Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Penghui Yang Penghui Yang Penghui Yang Penghui Yang Penghui Yang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Jie Tian Jie Tian Jie Tian Jie Tian Jie Tian Mi Li Mi Li Mi Li Mi Li Mi Li |
| author_facet | Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Penghui Yang Penghui Yang Penghui Yang Penghui Yang Penghui Yang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Jie Tian Jie Tian Jie Tian Jie Tian Jie Tian Mi Li Mi Li Mi Li Mi Li Mi Li |
| author_sort | Zhijun Wu |
| collection | DOAJ |
| description | Background: Arrhythmia is the most common complication after transcatheter closure of a ventricular septal defect (VSD). However, the effects of postprocedural left anterior fascicular block are not clear. This study presents the clinical characteristics, prognosis, and related risk factors of left anterior fascicular block after transcatheter closure of a VSD in children.Methods: The clinical and follow-up data of the patients in the Heart Center of Children's Hospital of Chongqing Medical University from June 2009 to October 2018 were reviewed. And 30 cases were eligible out of all 1,371 cases.Results: An electrocardiogram showed a left anterior fascicular block within 3 days, and most patients gradually returned to normal within 1–2 years, showing a dynamic change. Left ventricular end-diastolic dimension Z-score ranged from −2 to 2 in all children, and no decrease of left ventricular ejection fraction was found in all children. The high ratio between VSD size and body surface area [p < 0.05, odds ratio (OR) 2.6, 95% CI: 1.136–6.113] and large diameter difference between the occluder size and VSD size (p < 0.05, OR 2.1, 95% CI: 1.036–4.609) were independent risk factors for postprocedural left anterior fascicular block.Conclusions: The incidence of postprocedural left anterior fascicular block is not that low, and the overall prognosis is quite good at the current follow-up stage. No progressive severity has been found, such as complete left bundle branch block, double (triple) bundle branch block, and atrioventricular block, to have an influence on cardiac systolic and diastolic function. |
| first_indexed | 2024-12-17T06:35:34Z |
| format | Article |
| id | doaj.art-63ffbf0372d0401c9d50280ecce74738 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-17T06:35:34Z |
| publishDate | 2021-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-63ffbf0372d0401c9d50280ecce747382022-12-21T22:00:01ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-06-01810.3389/fcvm.2021.609531609531Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in ChildrenZhijun Wu0Zhijun Wu1Zhijun Wu2Zhijun Wu3Zhijun Wu4Penghui Yang5Penghui Yang6Penghui Yang7Penghui Yang8Penghui Yang9Ping Xiang10Ping Xiang11Ping Xiang12Ping Xiang13Ping Xiang14Xiaojuan Ji15Xiaojuan Ji16Xiaojuan Ji17Xiaojuan Ji18Xiaojuan Ji19Jie Tian20Jie Tian21Jie Tian22Jie Tian23Jie Tian24Mi Li25Mi Li26Mi Li27Mi Li28Mi Li29Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaDepartment of Ultrasound, Children's Hospital of Chongqing Medical University, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaMinistry of Education Key Laboratory of Child Development and Disorders, Chongqing, ChinaChina International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, ChinaDepartment of Cardiovascular Medicine, Children's Hospital of Chongqing Medical University, Chongqing, ChinaNational Clinical Research Center for Child Health and Disorders, Chongqing, ChinaChongqing Key Laboratory of Pediatrics, Chongqing, ChinaBackground: Arrhythmia is the most common complication after transcatheter closure of a ventricular septal defect (VSD). However, the effects of postprocedural left anterior fascicular block are not clear. This study presents the clinical characteristics, prognosis, and related risk factors of left anterior fascicular block after transcatheter closure of a VSD in children.Methods: The clinical and follow-up data of the patients in the Heart Center of Children's Hospital of Chongqing Medical University from June 2009 to October 2018 were reviewed. And 30 cases were eligible out of all 1,371 cases.Results: An electrocardiogram showed a left anterior fascicular block within 3 days, and most patients gradually returned to normal within 1–2 years, showing a dynamic change. Left ventricular end-diastolic dimension Z-score ranged from −2 to 2 in all children, and no decrease of left ventricular ejection fraction was found in all children. The high ratio between VSD size and body surface area [p < 0.05, odds ratio (OR) 2.6, 95% CI: 1.136–6.113] and large diameter difference between the occluder size and VSD size (p < 0.05, OR 2.1, 95% CI: 1.036–4.609) were independent risk factors for postprocedural left anterior fascicular block.Conclusions: The incidence of postprocedural left anterior fascicular block is not that low, and the overall prognosis is quite good at the current follow-up stage. No progressive severity has been found, such as complete left bundle branch block, double (triple) bundle branch block, and atrioventricular block, to have an influence on cardiac systolic and diastolic function.https://www.frontiersin.org/articles/10.3389/fcvm.2021.609531/fullventricular septal defecttranscatheter closureleft anterior fascicular blockarrhythmiaschildren |
| spellingShingle | Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Zhijun Wu Penghui Yang Penghui Yang Penghui Yang Penghui Yang Penghui Yang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Ping Xiang Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Xiaojuan Ji Jie Tian Jie Tian Jie Tian Jie Tian Jie Tian Mi Li Mi Li Mi Li Mi Li Mi Li Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children Frontiers in Cardiovascular Medicine ventricular septal defect transcatheter closure left anterior fascicular block arrhythmias children |
| title | Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children |
| title_full | Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children |
| title_fullStr | Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children |
| title_full_unstemmed | Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children |
| title_short | Left Anterior Fascicular Block After Transcatheter Closure of Ventricular Septal Defect in Children |
| title_sort | left anterior fascicular block after transcatheter closure of ventricular septal defect in children |
| topic | ventricular septal defect transcatheter closure left anterior fascicular block arrhythmias children |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2021.609531/full |
| work_keys_str_mv | AT zhijunwu leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT zhijunwu leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT zhijunwu leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT zhijunwu leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT zhijunwu leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT penghuiyang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT penghuiyang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT penghuiyang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT penghuiyang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT penghuiyang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT pingxiang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT pingxiang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT pingxiang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT pingxiang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT pingxiang leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT xiaojuanji leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT xiaojuanji leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT xiaojuanji leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT xiaojuanji leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT xiaojuanji leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT jietian leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT jietian leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT jietian leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT jietian leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT jietian leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT mili leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT mili leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT mili leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT mili leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren AT mili leftanteriorfascicularblockaftertranscatheterclosureofventricularseptaldefectinchildren |