MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE
Exposure to cigarette smoke can cause oxidative stress, which characterized by increased activity of g-GT serum. The skins of the mangosteen (Garcinia mangostana L.) contain anthocyanins pigments, which can act as antioxidants to reduce free radicals. This study mainly aims to investigate the effect...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Research and Community Service Department (LPPM) Universitas Wijaya Kusuma Surabaya
2017-06-01
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| Series: | Jurnal Ilmiah Kedokteran Wijaya Kusuma |
| Subjects: | |
| Online Access: | https://journal.uwks.ac.id/index.php/jikw/article/view/39 |
| _version_ | 1797728068842815488 |
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| author | Loo Hariyanto Raharjo Hwa Tjeen Anna Lewi Santoso |
| author_facet | Loo Hariyanto Raharjo Hwa Tjeen Anna Lewi Santoso |
| author_sort | Loo Hariyanto Raharjo |
| collection | DOAJ |
| description | Exposure to cigarette smoke can cause oxidative stress, which characterized by increased activity of g-GT serum. The skins of the mangosteen (Garcinia mangostana L.) contain anthocyanins pigments, which can act as antioxidants to reduce free radicals. This study mainly aims to investigate the effect of mangosteen skin extracts to decreased activity of g-GT serum in rats exposed to cigarette smoke. This study was true experimental designs with randomized post-test only control group design. This study used thirty male rats were dividing into six treatment groups. Rats exposed to cigarette smoke, which came from two cigarettes, for 4 weeks lead to an increase free radicals in the body. The increased activity of g-GT serum to damp the free radicals. Mangosteen skin extracts can reduce free radicals so that the activity of g-GT serum decreased.
The conclusion of this research is the mangosteen skin extracts can decrease the activity of the g-GT serum. |
| first_indexed | 2024-03-12T11:08:32Z |
| format | Article |
| id | doaj.art-6401382cecbc4614982d9a620f1a9282 |
| institution | Directory Open Access Journal |
| issn | 1978-2071 2580-5967 |
| language | English |
| last_indexed | 2024-03-12T11:08:32Z |
| publishDate | 2017-06-01 |
| publisher | Research and Community Service Department (LPPM) Universitas Wijaya Kusuma Surabaya |
| record_format | Article |
| series | Jurnal Ilmiah Kedokteran Wijaya Kusuma |
| spelling | doaj.art-6401382cecbc4614982d9a620f1a92822023-09-02T03:26:22ZengResearch and Community Service Department (LPPM) Universitas Wijaya Kusuma SurabayaJurnal Ilmiah Kedokteran Wijaya Kusuma1978-20712580-59672017-06-0131293939MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURELoo Hariyanto Raharjo0Hwa Tjeen Anna Lewi Santoso1Bagian Biokimia Fakultas Kedokteran Universitas Wijaya Kusuma SurabayaBagian Histologi Fakultas Kedokteran Universitas Wijaya Kusuma SurabayaExposure to cigarette smoke can cause oxidative stress, which characterized by increased activity of g-GT serum. The skins of the mangosteen (Garcinia mangostana L.) contain anthocyanins pigments, which can act as antioxidants to reduce free radicals. This study mainly aims to investigate the effect of mangosteen skin extracts to decreased activity of g-GT serum in rats exposed to cigarette smoke. This study was true experimental designs with randomized post-test only control group design. This study used thirty male rats were dividing into six treatment groups. Rats exposed to cigarette smoke, which came from two cigarettes, for 4 weeks lead to an increase free radicals in the body. The increased activity of g-GT serum to damp the free radicals. Mangosteen skin extracts can reduce free radicals so that the activity of g-GT serum decreased. The conclusion of this research is the mangosteen skin extracts can decrease the activity of the g-GT serum.https://journal.uwks.ac.id/index.php/jikw/article/view/39cigarette smoke, free radicals, activity of -GT serum, mangosteen skin extract |
| spellingShingle | Loo Hariyanto Raharjo Hwa Tjeen Anna Lewi Santoso MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE Jurnal Ilmiah Kedokteran Wijaya Kusuma cigarette smoke, free radicals, activity of -GT serum, mangosteen skin extract |
| title | MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE |
| title_full | MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE |
| title_fullStr | MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE |
| title_full_unstemmed | MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE |
| title_short | MANGOSTEEN SKIN EXTRACTS DECREASE THE ACTIVITY OF THE GAMMA-GLUTAMYLTRANSFERASE (-GT) SERUM ON THE CIGARETTE EXPOSURE |
| title_sort | mangosteen skin extracts decrease the activity of the gamma glutamyltransferase gt serum on the cigarette exposure |
| topic | cigarette smoke, free radicals, activity of -GT serum, mangosteen skin extract |
| url | https://journal.uwks.ac.id/index.php/jikw/article/view/39 |
| work_keys_str_mv | AT loohariyantoraharjo mangosteenskinextractsdecreasetheactivityofthegammaglutamyltransferasegtserumonthecigaretteexposure AT hwatjeenannalewisantoso mangosteenskinextractsdecreasetheactivityofthegammaglutamyltransferasegtserumonthecigaretteexposure |