Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review

Over recent years, the usage of autologous platelet concentrates (APCs) has risen in hard tissue regeneration and oral implantology. The purpose of the present review is to offer an overview of the use of three APC techniques in dentistry: platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and...

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Main Authors: Eitan Mijiritsky, Haya Drora Assaf, Roni Kolerman, Luca Mangani, Vasilena Ivanova, Stefan Zlatev
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/11/9/1254
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author Eitan Mijiritsky
Haya Drora Assaf
Roni Kolerman
Luca Mangani
Vasilena Ivanova
Stefan Zlatev
author_facet Eitan Mijiritsky
Haya Drora Assaf
Roni Kolerman
Luca Mangani
Vasilena Ivanova
Stefan Zlatev
author_sort Eitan Mijiritsky
collection DOAJ
description Over recent years, the usage of autologous platelet concentrates (APCs) has risen in hard tissue regeneration and oral implantology. The purpose of the present review is to offer an overview of the use of three APC techniques in dentistry: platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and concentrated growth factor (CGF). A narrative summary of articles published between January 2011 and April 2022 is provided. The PubMed, Cochrane Library, Scopus, and Embase databases were used to conduct the search. The following keywords were used in the preliminary: “VEGF”, “TGF-b1”, “PRP”, “PRF”, “CGF”, AND “sinus augmentation” OR “implants” OR “peri-implantitis” OR “socket preservation” OR “MRONJ”. A total of 82 articles was finally included. The review then takes into account the application of the three techniques in different areas of treatment—including oral implantology, sinus floor elevation, peri-implantitis, socket preservation, and medication-related osteonecrosis of the jaw (MRONJ)—as well as their advantages and disadvantages.
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spelling doaj.art-64014ad0bde74a1cab9f516e54d833c82023-11-23T15:06:27ZengMDPI AGBiology2079-77372022-08-01119125410.3390/biology11091254Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature ReviewEitan Mijiritsky0Haya Drora Assaf1Roni Kolerman2Luca Mangani3Vasilena Ivanova4Stefan Zlatev5Head and Neck Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Department of Otolaryngology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 699350, IsraelFaculty of Dental Medicine, Hebrew University of Jerusalem, Jerusalem 9190401, IsraelDepartment of Periodontology and Oral Implantology, The Maurice and Gabriela Goldschleger School of Dental Medicine, Tel-Aviv University, Tel-Aviv 6997801, IsraelDepartment of Translational Medicine and Clinical Science, University of Tor Vegata, 00133 Rome, ItalyOral Surgery Department, Faculty of Dental Medicine, Medical University of Plovdiv, 4000 Plovdiv, BulgariaCAD/CAM Center of Dental Medicine at the Research Institute, Medical University-Plovdiv, 4000 Plovdiv, BulgariaOver recent years, the usage of autologous platelet concentrates (APCs) has risen in hard tissue regeneration and oral implantology. The purpose of the present review is to offer an overview of the use of three APC techniques in dentistry: platelet-rich plasma (PRP), platelet-rich fibrin (PRF), and concentrated growth factor (CGF). A narrative summary of articles published between January 2011 and April 2022 is provided. The PubMed, Cochrane Library, Scopus, and Embase databases were used to conduct the search. The following keywords were used in the preliminary: “VEGF”, “TGF-b1”, “PRP”, “PRF”, “CGF”, AND “sinus augmentation” OR “implants” OR “peri-implantitis” OR “socket preservation” OR “MRONJ”. A total of 82 articles was finally included. The review then takes into account the application of the three techniques in different areas of treatment—including oral implantology, sinus floor elevation, peri-implantitis, socket preservation, and medication-related osteonecrosis of the jaw (MRONJ)—as well as their advantages and disadvantages.https://www.mdpi.com/2079-7737/11/9/1254PRFPRPCGFautologous platelet concentratesbone regenerationdental implants
spellingShingle Eitan Mijiritsky
Haya Drora Assaf
Roni Kolerman
Luca Mangani
Vasilena Ivanova
Stefan Zlatev
Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
Biology
PRF
PRP
CGF
autologous platelet concentrates
bone regeneration
dental implants
title Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
title_full Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
title_fullStr Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
title_full_unstemmed Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
title_short Autologous Platelet Concentrates (APCs) for Hard Tissue Regeneration in Oral Implantology, Sinus Floor Elevation, Peri-Implantitis, Socket Preservation, and Medication-Related Osteonecrosis of the Jaw (MRONJ): A Literature Review
title_sort autologous platelet concentrates apcs for hard tissue regeneration in oral implantology sinus floor elevation peri implantitis socket preservation and medication related osteonecrosis of the jaw mronj a literature review
topic PRF
PRP
CGF
autologous platelet concentrates
bone regeneration
dental implants
url https://www.mdpi.com/2079-7737/11/9/1254
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