Caveolin-1 is a primary determinant of endothelial stiffening associated with dyslipidemia, disturbed flow, and ageing

Abstract Endothelial stiffness is emerging as a major determinant in endothelial function. Here, we analyzed the role of caveolin-1 (Cav-1) in determining the stiffness of endothelial cells (EC) exposed to oxidized low density lipoprotein (oxLDL) under static and hemodynamic conditions in vitro and...

Full description

Bibliographic Details
Main Authors: Elizabeth Le Master, Amit Paul, Dana Lazarko, Victor Aguilar, Sang Joon Ahn, James C. Lee, Richard D. Minshall, Irena Levitan
Format: Article
Language:English
Published: Nature Portfolio 2022-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-20713-7

Similar Items