Brucella Infection in HIV Infected Patients
The purpose of this study was to assess the possible correlation between Brucella and HIV infections. Iran is a country where HIV infection is expanding and Brucellosis is prevalent. In the present study, 184 HIV infected patients were assigned and for all of them HIV infection was confirmed by west...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2011-12-01
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| Series: | Acta Medica Iranica |
| Subjects: | |
| Online Access: | https://acta.tums.ac.ir/index.php/acta/article/view/3842 |
| _version_ | 1811297549760331776 |
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| author | Mahboubeh Hajiabdolbaghi Maryam Rasoulinejad Alireza Abdollahi Koosha Paydary Pegah Valiollahi SeyedAhmad SeyedAlinaghi Maziar Parsa Sirous Jafari |
| author_facet | Mahboubeh Hajiabdolbaghi Maryam Rasoulinejad Alireza Abdollahi Koosha Paydary Pegah Valiollahi SeyedAhmad SeyedAlinaghi Maziar Parsa Sirous Jafari |
| author_sort | Mahboubeh Hajiabdolbaghi |
| collection | DOAJ |
| description | The purpose of this study was to assess the possible correlation between Brucella and HIV infections. Iran is a country where HIV infection is expanding and Brucellosis is prevalent. In the present study, 184 HIV infected patients were assigned and for all of them HIV infection was confirmed by western blot test. In order to identify the prevalence rate of Brucella infection and systemic brucellosis in these subjects, sera samples were obtained and Brucella specific serological tests were performed to reveal antibody titers. Detailed history was taken and physical examination was carried out for all of patients. 11 (6%) subjects had high titers but only 3 of them were symptomatic. Most of these subjects were injection drug user (IDU) men and one was a rural woman. Considering both prevalence rates of Brucella infection (3%) and symptomatic brucellosis (0.1%) in Iran, our HIV positive patients show higher rates of Brucella infection and systemic brucellosis. Preserved cellular immunity of participants and retention of granulocytes activity may explain this poor association; whereas other explanations such as immunological state difference and non-overlapping geographical distribution of the 2 pathogens have been mentioned by various authors. |
| first_indexed | 2024-04-13T06:07:01Z |
| format | Article |
| id | doaj.art-6403bdf18454466fb541a20d2d7d1c1a |
| institution | Directory Open Access Journal |
| issn | 0044-6025 1735-9694 |
| language | English |
| last_indexed | 2024-04-13T06:07:01Z |
| publishDate | 2011-12-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Acta Medica Iranica |
| spelling | doaj.art-6403bdf18454466fb541a20d2d7d1c1a2022-12-22T02:59:14ZengTehran University of Medical SciencesActa Medica Iranica0044-60251735-96942011-12-014912Brucella Infection in HIV Infected PatientsMahboubeh Hajiabdolbaghi0Maryam Rasoulinejad1Alireza Abdollahi2Koosha Paydary3Pegah Valiollahi4SeyedAhmad SeyedAlinaghi5Maziar Parsa6Sirous Jafari7Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.Iranian Research Center for HIV/AIDS (IRCHA), Tehran University of Medical Sciences, Tehran, Iran.The purpose of this study was to assess the possible correlation between Brucella and HIV infections. Iran is a country where HIV infection is expanding and Brucellosis is prevalent. In the present study, 184 HIV infected patients were assigned and for all of them HIV infection was confirmed by western blot test. In order to identify the prevalence rate of Brucella infection and systemic brucellosis in these subjects, sera samples were obtained and Brucella specific serological tests were performed to reveal antibody titers. Detailed history was taken and physical examination was carried out for all of patients. 11 (6%) subjects had high titers but only 3 of them were symptomatic. Most of these subjects were injection drug user (IDU) men and one was a rural woman. Considering both prevalence rates of Brucella infection (3%) and symptomatic brucellosis (0.1%) in Iran, our HIV positive patients show higher rates of Brucella infection and systemic brucellosis. Preserved cellular immunity of participants and retention of granulocytes activity may explain this poor association; whereas other explanations such as immunological state difference and non-overlapping geographical distribution of the 2 pathogens have been mentioned by various authors.https://acta.tums.ac.ir/index.php/acta/article/view/3842BrucellaHIV infectionBrucellosis |
| spellingShingle | Mahboubeh Hajiabdolbaghi Maryam Rasoulinejad Alireza Abdollahi Koosha Paydary Pegah Valiollahi SeyedAhmad SeyedAlinaghi Maziar Parsa Sirous Jafari Brucella Infection in HIV Infected Patients Acta Medica Iranica Brucella HIV infection Brucellosis |
| title | Brucella Infection in HIV Infected Patients |
| title_full | Brucella Infection in HIV Infected Patients |
| title_fullStr | Brucella Infection in HIV Infected Patients |
| title_full_unstemmed | Brucella Infection in HIV Infected Patients |
| title_short | Brucella Infection in HIV Infected Patients |
| title_sort | brucella infection in hiv infected patients |
| topic | Brucella HIV infection Brucellosis |
| url | https://acta.tums.ac.ir/index.php/acta/article/view/3842 |
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