Marine Organisms as a Prolific Source of Bioactive Depsipeptides

Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine. A growing body of evidence demonstrates that marine organisms are prolific sources of depsipeptide...

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Bibliographic Details
Main Authors: Mingyuan Zeng, Jianyun Tao, Shuang Xu, Xuelian Bai, Huawei Zhang
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Marine Drugs
Subjects:
Online Access:https://www.mdpi.com/1660-3397/21/2/120
Description
Summary:Depsipeptides, an important group of polypeptides containing residues of hydroxy acids and amino acids linked together by amide and ester bonds, have potential applications in agriculture and medicine. A growing body of evidence demonstrates that marine organisms are prolific sources of depsipeptides, such as marine cyanobacteria, sponges, mollusks, microorganisms and algae. However, these substances have not yet been comprehensively summarized. In order to enrich our knowledge about marine depsipeptides, their biological sources and structural features, as well as bioactivities, are highlighted in this review after an extensive literature search and data analysis.
ISSN:1660-3397