Single-Nucleotide Polymorphisms (SNPs) Both Associated with Hypertension and Contributing to Accelerated-Senescence Traits in OXYS Rats
Aging is a major risk factor of numerous human diseases. Adverse genetic variants may contribute to multiple manifestations of aging and increase the number of comorbid conditions. There is evidence of links between hypertension and age-related diseases, although the genetic relationships are insuff...
Main Authors: | Vasiliy A. Devyatkin, Olga E. Redina, Natalia A. Muraleva, Nataliya G. Kolosova |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2020-05-01
|
Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/21/10/3542 |
Similar Items
-
Quantitative Metabolomic Analysis of Changes in the Rat Blood Serum during Autophagy Modulation: A Focus on Accelerated Senescence
by: Olga Snytnikova, et al.
Published: (2022-10-01) -
P38 MAPK Signaling in the Retina: Effects of Aging and Age-Related Macular Degeneration
by: Natalia A. Muraleva, et al.
Published: (2023-07-01) -
MEK1/2-ERK Pathway Alterations as a Therapeutic Target in Sporadic Alzheimer’s Disease: A Study in Senescence-Accelerated OXYS Rats
by: Natalia A. Muraleva, et al.
Published: (2021-06-01) -
Association of cerebrovascular dysfunction with the development of Alzheimer’s disease-like pathology in OXYS rats
by: Natalia A. Stefanova, et al.
Published: (2018-02-01) -
Postnatal Maturation of the Blood–Brain Barrier in Senescence-Accelerated OXYS Rats, Which Are Prone to an Alzheimer’s Disease-like Pathology
by: Ekaterina Rudnitskaya, et al.
Published: (2023-10-01)