Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

Morphology of ovaries in laron dwarf mice, with low circulating plasma levels of insulin-like growth factor-1 (IGF-1), and in bovine GH-transgenic mice, with high circulating plasma levels of IGF-1

<p>Abstract</p> <p>Background</p> <p>It is well known that somatotrophic/insulin signaling affects lifespan in experimental animals, and one of the signs of aging is progressive gonadal dysfunction.</p> <p>Methods</p> <p>To study the effects of i...

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Bibliographic Details
Main Authors: Słuczanowska-Głąbowska Sylwia, Laszczyńska Maria, Piotrowska Katarzyna, Głąbowski Wojciech, Kopchick John J, Bartke Andrzej, Kucia Magda, Ratajczak Mariusz Z
Format: Article
Language:English
Published: BMC 2012-07-01
Series:Journal of Ovarian Research
Subjects:
Murine ovary
Laron dwarf mouse
Bovine growth hormone transgenic mouse
Growth hormone
Insulin-like growth factor-1
Aging
Online Access:http://www.ovarianresearch.com/content/5/1/18

Internet

http://www.ovarianresearch.com/content/5/1/18

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