An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer
Oral and pharyngeal cancers are some of the most common cancers worldwide. The risk of developing oral cancer is modified by environment, lifestyle, genetics, and a combination of these factors. Both environmental carcinogens and polymorphisms together or individually play an important role in the p...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | SRM Journal of Research in Dental Sciences |
| Subjects: | |
| Online Access: | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=4;spage=269;epage=273;aulast=Sangeetha |
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| author | Jeevankumar Sangeetha Annasamy Rameshkumar Ramadas Ramya Padmanaban Rajashree Krishnan Rajkumar |
| author_facet | Jeevankumar Sangeetha Annasamy Rameshkumar Ramadas Ramya Padmanaban Rajashree Krishnan Rajkumar |
| author_sort | Jeevankumar Sangeetha |
| collection | DOAJ |
| description | Oral and pharyngeal cancers are some of the most common cancers worldwide. The risk of developing oral cancer is modified by environment, lifestyle, genetics, and a combination of these factors. Both environmental carcinogens and polymorphisms together or individually play an important role in the pathogenesis of oral and pharyngeal cancer. Various genes show polymorphisms, which are thought to play a major role in interindividual variability in drug response, and in susceptibility to chemical induced diseases, like several types of cancers. The objective of this review is to discuss in detail about the various polymorphism, molecular functions and the polymorphic association of various genes. |
| first_indexed | 2024-04-12T01:00:04Z |
| format | Article |
| id | doaj.art-640acbb6a2ce43818091a27d537988a4 |
| institution | Directory Open Access Journal |
| issn | 2772-5243 2772-5251 |
| language | English |
| last_indexed | 2024-04-12T01:00:04Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | SRM Journal of Research in Dental Sciences |
| spelling | doaj.art-640acbb6a2ce43818091a27d537988a42022-12-22T03:54:30ZengWolters Kluwer Medknow PublicationsSRM Journal of Research in Dental Sciences2772-52432772-52512014-01-015426927310.4103/0976-433X.145154An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancerJeevankumar SangeethaAnnasamy RameshkumarRamadas RamyaPadmanaban RajashreeKrishnan RajkumarOral and pharyngeal cancers are some of the most common cancers worldwide. The risk of developing oral cancer is modified by environment, lifestyle, genetics, and a combination of these factors. Both environmental carcinogens and polymorphisms together or individually play an important role in the pathogenesis of oral and pharyngeal cancer. Various genes show polymorphisms, which are thought to play a major role in interindividual variability in drug response, and in susceptibility to chemical induced diseases, like several types of cancers. The objective of this review is to discuss in detail about the various polymorphism, molecular functions and the polymorphic association of various genes.http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=4;spage=269;epage=273;aulast=Sangeethamicrosatelliteminisatellitepolymorphismtandem repeatsxenobiotics |
| spellingShingle | Jeevankumar Sangeetha Annasamy Rameshkumar Ramadas Ramya Padmanaban Rajashree Krishnan Rajkumar An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer SRM Journal of Research in Dental Sciences microsatellite minisatellite polymorphism tandem repeats xenobiotics |
| title | An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| title_full | An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| title_fullStr | An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| title_full_unstemmed | An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| title_short | An insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| title_sort | insight of genetic polymorphism and the commonly studied polymorphisms associated with oral cancer |
| topic | microsatellite minisatellite polymorphism tandem repeats xenobiotics |
| url | http://www.srmjrds.in/article.asp?issn=0976-433X;year=2014;volume=5;issue=4;spage=269;epage=273;aulast=Sangeetha |
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