Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram

Background: This work is a part of a new concept. The aim is to study the measurements that can be used as input to an intelligent system for detecting cerebral malaria from an electroencephalogram (EEG). Materials and Methods: The study of brain connectivity through the calculation of the phase lag...

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Main Authors: Temgoua Nanfack Pelagie Flore, Jean Marie Kuate Fotso, Bénite Isaoura, Patrice Abiama Ele
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Current Medicine Research and Practice
Subjects:
Online Access:http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2020;volume=10;issue=5;spage=210;epage=214;aulast=Pelagie
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author Temgoua Nanfack Pelagie Flore
Jean Marie Kuate Fotso
Bénite Isaoura
Patrice Abiama Ele
author_facet Temgoua Nanfack Pelagie Flore
Jean Marie Kuate Fotso
Bénite Isaoura
Patrice Abiama Ele
author_sort Temgoua Nanfack Pelagie Flore
collection DOAJ
description Background: This work is a part of a new concept. The aim is to study the measurements that can be used as input to an intelligent system for detecting cerebral malaria from an electroencephalogram (EEG). Materials and Methods: The study of brain connectivity through the calculation of the phase lag index, which is an adjacency matrix, allows evaluating the units such as degree, density and strength on each channel. These units were evaluated on 29 EEG recordings, consisting of twenty people suffering from coma and nine healthy individuals. Results: Considering analysis of variance with two factors that are frequency band and group (patient and healthy control), the degree and the density are always higher in healthy children compared to sick children. Nevertheless, the strength is always higher in healthy children compared to sick children with the exception of the delta band on which the values are equal and the alpha band on which the strength is higher in sick children by the report to healthy children. Conclusion: There is a significant difference (P = 0.002) between the strength of sick people compared to healthy people. Such technology could help reduce the death rate from malaria, in general, and cerebral malaria, in particular, especially in sub-Saharan Africa where this rate is very high.
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spelling doaj.art-640d49eb554840f4b66d3250e23615e92022-12-22T02:49:49ZengWolters Kluwer Medknow PublicationsCurrent Medicine Research and Practice2352-08172352-08252020-01-0110521021410.4103/cmrp.cmrp_17_20Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogramTemgoua Nanfack Pelagie FloreJean Marie Kuate FotsoBénite IsaouraPatrice Abiama EleBackground: This work is a part of a new concept. The aim is to study the measurements that can be used as input to an intelligent system for detecting cerebral malaria from an electroencephalogram (EEG). Materials and Methods: The study of brain connectivity through the calculation of the phase lag index, which is an adjacency matrix, allows evaluating the units such as degree, density and strength on each channel. These units were evaluated on 29 EEG recordings, consisting of twenty people suffering from coma and nine healthy individuals. Results: Considering analysis of variance with two factors that are frequency band and group (patient and healthy control), the degree and the density are always higher in healthy children compared to sick children. Nevertheless, the strength is always higher in healthy children compared to sick children with the exception of the delta band on which the values are equal and the alpha band on which the strength is higher in sick children by the report to healthy children. Conclusion: There is a significant difference (P = 0.002) between the strength of sick people compared to healthy people. Such technology could help reduce the death rate from malaria, in general, and cerebral malaria, in particular, especially in sub-Saharan Africa where this rate is very high.http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2020;volume=10;issue=5;spage=210;epage=214;aulast=Pelagieelectroencephalography; plasmodium falciparum; brain malaria; anova; phase lag index (pli)
spellingShingle Temgoua Nanfack Pelagie Flore
Jean Marie Kuate Fotso
Bénite Isaoura
Patrice Abiama Ele
Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
Current Medicine Research and Practice
electroencephalography; plasmodium falciparum; brain malaria; anova; phase lag index (pli)
title Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
title_full Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
title_fullStr Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
title_full_unstemmed Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
title_short Intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
title_sort intelligent system for early diagnosis of paediatric cerebral malaria from an electroencephalogram
topic electroencephalography; plasmodium falciparum; brain malaria; anova; phase lag index (pli)
url http://www.cmrpjournal.org/article.asp?issn=2352-0817;year=2020;volume=10;issue=5;spage=210;epage=214;aulast=Pelagie
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AT beniteisaoura intelligentsystemforearlydiagnosisofpaediatriccerebralmalariafromanelectroencephalogram
AT patriceabiamaele intelligentsystemforearlydiagnosisofpaediatriccerebralmalariafromanelectroencephalogram