Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice

Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice

BackgroundToxoplasma gondii can cause congenital infection and abortion in humans and warm-blooded animals. T. gondii dense granule proteins, GRA35, GRA42, and GRA43, play a critical role in the establishment of chronic infection. However, their potential to induce protective immunity against T. gon...

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Bibliographic Details
Main Authors: Youbo Shi, Jianbing Li, Weili Yang, Jia Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Toxoplasma gondii
GRA35
GRA42
GRA43
DNA vaccine
protective immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2023.1236130/full

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