Machine learning and expression analyses reveal circadian clock features predictive of anxiety
Abstract Mood disorders, including generalized anxiety disorder, are associated with disruptions in circadian rhythms and are linked to polymorphisms in circadian clock genes. Molecular mechanisms underlying these connections may be direct—via transcriptional activity of clock genes on downstream mo...
Main Authors: | Aziz Zafar, Rebeccah Overton, Ziad Attia, Ahmet Ay, Krista Ingram |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-09421-4 |
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