Machine learning and expression analyses reveal circadian clock features predictive of anxiety

Abstract Mood disorders, including generalized anxiety disorder, are associated with disruptions in circadian rhythms and are linked to polymorphisms in circadian clock genes. Molecular mechanisms underlying these connections may be direct—via transcriptional activity of clock genes on downstream mo...

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Bibliographic Details
Main Authors: Aziz Zafar, Rebeccah Overton, Ziad Attia, Ahmet Ay, Krista Ingram
Format: Article
Language:English
Published: Nature Portfolio 2022-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-09421-4

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