Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC

Cervical cancer is the fourth most common malignancy in women in the world; however, a substantial portion of these malignancies are declining with increasingly sophisticated screening. Unfortunately, recurrent cervical cancer has a dismal prognosis and its management continues to be a growing area...

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Main Authors: Taliya Lantsman, Marcos Lepe, Leslie Garrett, Martin Goodman, Meghan Shea
Format: Article
Language:English
Published: Elsevier 2022-02-01
Series:Gynecologic Oncology Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352578921002137
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author Taliya Lantsman
Marcos Lepe
Leslie Garrett
Martin Goodman
Meghan Shea
author_facet Taliya Lantsman
Marcos Lepe
Leslie Garrett
Martin Goodman
Meghan Shea
author_sort Taliya Lantsman
collection DOAJ
description Cervical cancer is the fourth most common malignancy in women in the world; however, a substantial portion of these malignancies are declining with increasingly sophisticated screening. Unfortunately, recurrent cervical cancer has a dismal prognosis and its management continues to be a growing area of research. While the foundation of treatment remains platinum-based chemotherapies, new techniques such as HIPEC have been evaluated. We present two patients with recurrent cervical adenocarcinoma with peritoneal carcinomatosis who were treated with HIPEC during de-bulking surgery with substantial disease-free survival.One of our patients had 15 months of disease-free survival before developing biliary metastases and the other remains disease free for over 24 months.
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spelling doaj.art-64169c243951407280f1431ebe846f7a2022-12-21T17:59:25ZengElsevierGynecologic Oncology Reports2352-57892022-02-0139100909Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPECTaliya Lantsman0Marcos Lepe1Leslie Garrett2Martin Goodman3Meghan Shea4Department of Internal Medicine, Beth Israel Deaconess Medical Center, United States; Corresponding author at: Beth Israel Deaconess Medical Center, Deaconess Building, Suite 306, One Deaconess Road, Boston, MA 02215, United States.Department of Clinical Pathology, Beth Israel Deaconess Medical Center, United StatesDepartment of Gynecologic Oncology, Beth Israel Deaconess Medical Center, United StatesDepartment of Surgical Oncology, Tufts University School of Medicine, United StatesDepartment of Oncology, Beth Israel Deaconess Medical Center, United StatesCervical cancer is the fourth most common malignancy in women in the world; however, a substantial portion of these malignancies are declining with increasingly sophisticated screening. Unfortunately, recurrent cervical cancer has a dismal prognosis and its management continues to be a growing area of research. While the foundation of treatment remains platinum-based chemotherapies, new techniques such as HIPEC have been evaluated. We present two patients with recurrent cervical adenocarcinoma with peritoneal carcinomatosis who were treated with HIPEC during de-bulking surgery with substantial disease-free survival.One of our patients had 15 months of disease-free survival before developing biliary metastases and the other remains disease free for over 24 months.http://www.sciencedirect.com/science/article/pii/S2352578921002137Recurrent cervical cancerHIPECPeritoneal carcinomatosis
spellingShingle Taliya Lantsman
Marcos Lepe
Leslie Garrett
Martin Goodman
Meghan Shea
Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
Gynecologic Oncology Reports
Recurrent cervical cancer
HIPEC
Peritoneal carcinomatosis
title Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
title_full Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
title_fullStr Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
title_full_unstemmed Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
title_short Management of recurrent cervical cancer with peritoneal carcinomatosis with HIPEC
title_sort management of recurrent cervical cancer with peritoneal carcinomatosis with hipec
topic Recurrent cervical cancer
HIPEC
Peritoneal carcinomatosis
url http://www.sciencedirect.com/science/article/pii/S2352578921002137
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AT lesliegarrett managementofrecurrentcervicalcancerwithperitonealcarcinomatosiswithhipec
AT martingoodman managementofrecurrentcervicalcancerwithperitonealcarcinomatosiswithhipec
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