Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis
The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric a-allylation of carbonyl compounds, a-fluorination of acyl derivatives, decarboxylative prot...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-08-01
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| Series: | Molecules |
| Subjects: | |
| Online Access: | http://www.mdpi.com/1420-3049/18/9/10108 |
| _version_ | 1818905937147068416 |
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| author | Isidro M. Pastor Diego A. Alonso Beatriz Maciá M. Ángeles Fernández-Ibañez |
| author_facet | Isidro M. Pastor Diego A. Alonso Beatriz Maciá M. Ángeles Fernández-Ibañez |
| author_sort | Isidro M. Pastor |
| collection | DOAJ |
| description | The dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric a-allylation of carbonyl compounds, a-fluorination of acyl derivatives, decarboxylative protonation of β-dicarbonyl compounds, cyclization reactions of alkynyl carbonyl compounds and β-functionalization of aldehydes have been efficiently achieved employing this double-catalytic methodology. |
| first_indexed | 2024-12-19T21:31:16Z |
| format | Article |
| id | doaj.art-641c278351904b8e92d7f2865d54dd11 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-12-19T21:31:16Z |
| publishDate | 2013-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-641c278351904b8e92d7f2865d54dd112022-12-21T20:04:54ZengMDPI AGMolecules1420-30492013-08-01189101081012110.3390/molecules180910108Palladium and Organocatalysis: An Excellent Recipe for Asymmetric SynthesisIsidro M. PastorDiego A. AlonsoBeatriz MaciáM. Ángeles Fernández-IbañezThe dual activation of simple substrates by the combination of organocatalysis and palladium catalysis has been successfully applied in a variety of different asymmetric transformations. Thus, the asymmetric a-allylation of carbonyl compounds, a-fluorination of acyl derivatives, decarboxylative protonation of β-dicarbonyl compounds, cyclization reactions of alkynyl carbonyl compounds and β-functionalization of aldehydes have been efficiently achieved employing this double-catalytic methodology.http://www.mdpi.com/1420-3049/18/9/10108palladiumorganocatalysisasymmetric synthesisdual activationtandem reactionallylationfluorinationdecarboxylative protonation |
| spellingShingle | Isidro M. Pastor Diego A. Alonso Beatriz Maciá M. Ángeles Fernández-Ibañez Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis Molecules palladium organocatalysis asymmetric synthesis dual activation tandem reaction allylation fluorination decarboxylative protonation |
| title | Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis |
| title_full | Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis |
| title_fullStr | Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis |
| title_full_unstemmed | Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis |
| title_short | Palladium and Organocatalysis: An Excellent Recipe for Asymmetric Synthesis |
| title_sort | palladium and organocatalysis an excellent recipe for asymmetric synthesis |
| topic | palladium organocatalysis asymmetric synthesis dual activation tandem reaction allylation fluorination decarboxylative protonation |
| url | http://www.mdpi.com/1420-3049/18/9/10108 |
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