Epidemiology and Characteristics of SARS-CoV-2 Variants of Concern: The Impacts of the Spike Mutations

Epidemiology and Characteristics of SARS-CoV-2 Variants of Concern: The Impacts of the Spike Mutations

SARS-CoV-2 expresses on its surface the Spike protein responsible for binding with the ACE2 receptor and which carries the majority of immunodominant epitopes. Mutations mainly affect this protein and can modify characteristics of the virus, giving each variant a unique profile concerning its transm...

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Bibliographic Details
Main Authors: Théophile Cocherie, Karen Zafilaza, Valentin Leducq, Stéphane Marot, Vincent Calvez, Anne-Geneviève Marcelin, Eve Todesco
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Microorganisms
Subjects:
SARS-CoV-2
COVID-19
Spike glycoprotein
immune evasion
transmissibility
Online Access:https://www.mdpi.com/2076-2607/11/1/30

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