The Antioxidant Potential of Graviola and Its Potential Medicinal Application
Graviola (<i>Annunona muricata</i> L.), a plant growing in tropical regions, has many names and a range of ethnomedicinal uses. The leaves are used to treat insomnia, diabetes, cystitis, and headaches, the crushed seeds have anthelmintic properties, and the fruits are used in the prepara...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Nutrients |
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| Online Access: | https://www.mdpi.com/2072-6643/15/2/402 |
| _version_ | 1797438049219510272 |
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| author | Beata Olas |
| author_facet | Beata Olas |
| author_sort | Beata Olas |
| collection | DOAJ |
| description | Graviola (<i>Annunona muricata</i> L.), a plant growing in tropical regions, has many names and a range of ethnomedicinal uses. The leaves are used to treat insomnia, diabetes, cystitis, and headaches, the crushed seeds have anthelmintic properties, and the fruits are used in the preparation of ice creams, candy, syrups, shakes, and other beverages. The key active components are believed to be annonaceous acetogenins, with more than 100 such compounds having been isolated from <i>A. muricata</i>. The plant is also a source of a range of phenolic compounds, essential oils, alkaloids, flavonol triglycosides, and megastigmanes, together with various minerals, including Mg, Fe, Cu, K, and Ca. Its key phenolic compounds are rutin, kaempferol, and quercetin. This paper provides an overview of the current state of knowledge about the antioxidant properties of various graviola organs and their major constituents, based on a review of various electronic databases. However, few findings have been obtained from clinical trials, and few in vitro and animal studies suggest that graviola preparations have antioxidant properties; as such, the antioxidant potential of graviola, and its safety, remain unclear. |
| first_indexed | 2024-03-09T11:31:32Z |
| format | Article |
| id | doaj.art-641e12b3154d43b68c7777a500ccd145 |
| institution | Directory Open Access Journal |
| issn | 2072-6643 |
| language | English |
| last_indexed | 2024-03-09T11:31:32Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nutrients |
| spelling | doaj.art-641e12b3154d43b68c7777a500ccd1452023-11-30T23:51:10ZengMDPI AGNutrients2072-66432023-01-0115240210.3390/nu15020402The Antioxidant Potential of Graviola and Its Potential Medicinal ApplicationBeata Olas0Department of General Biochemistry, Faculty of Biology and Environmental Protection, University of Lodz, Pomorska 141/3, 90-236 Lodz, PolandGraviola (<i>Annunona muricata</i> L.), a plant growing in tropical regions, has many names and a range of ethnomedicinal uses. The leaves are used to treat insomnia, diabetes, cystitis, and headaches, the crushed seeds have anthelmintic properties, and the fruits are used in the preparation of ice creams, candy, syrups, shakes, and other beverages. The key active components are believed to be annonaceous acetogenins, with more than 100 such compounds having been isolated from <i>A. muricata</i>. The plant is also a source of a range of phenolic compounds, essential oils, alkaloids, flavonol triglycosides, and megastigmanes, together with various minerals, including Mg, Fe, Cu, K, and Ca. Its key phenolic compounds are rutin, kaempferol, and quercetin. This paper provides an overview of the current state of knowledge about the antioxidant properties of various graviola organs and their major constituents, based on a review of various electronic databases. However, few findings have been obtained from clinical trials, and few in vitro and animal studies suggest that graviola preparations have antioxidant properties; as such, the antioxidant potential of graviola, and its safety, remain unclear.https://www.mdpi.com/2072-6643/15/2/402antioxidantgraviolaoxidative stress |
| spellingShingle | Beata Olas The Antioxidant Potential of Graviola and Its Potential Medicinal Application Nutrients antioxidant graviola oxidative stress |
| title | The Antioxidant Potential of Graviola and Its Potential Medicinal Application |
| title_full | The Antioxidant Potential of Graviola and Its Potential Medicinal Application |
| title_fullStr | The Antioxidant Potential of Graviola and Its Potential Medicinal Application |
| title_full_unstemmed | The Antioxidant Potential of Graviola and Its Potential Medicinal Application |
| title_short | The Antioxidant Potential of Graviola and Its Potential Medicinal Application |
| title_sort | antioxidant potential of graviola and its potential medicinal application |
| topic | antioxidant graviola oxidative stress |
| url | https://www.mdpi.com/2072-6643/15/2/402 |
| work_keys_str_mv | AT beataolas theantioxidantpotentialofgraviolaanditspotentialmedicinalapplication AT beataolas antioxidantpotentialofgraviolaanditspotentialmedicinalapplication |