Acute exacerbations of COPD: risk factors for failure and relapse
Marco Mantero,1,2 Paola Rogliani,3 Marta Di Pasquale,1,2 Eva Polverino,4 Ernesto Crisafulli,5 Monica Guerrero,6 Andrea Gramegna,1,2 Mario Cazzola,3 Francesco Blasi1,2 1Department of Pathophysiology and Transplantation, Università degli Studi di Milano, 2Internal Medicine Department, Resp...
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Format: | Article |
Language: | English |
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Dove Medical Press
2017-09-01
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Series: | International Journal of COPD |
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Online Access: | https://www.dovepress.com/acute-exacerbations-of-copd-risk-factors-for-failure-and-relapse-peer-reviewed-article-COPD |
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author | Mantero M Rogliani P Di Pasquale M Polverino E Crisafulli E Guerrero M Gramegna A Cazzola M Blasi F |
author_facet | Mantero M Rogliani P Di Pasquale M Polverino E Crisafulli E Guerrero M Gramegna A Cazzola M Blasi F |
author_sort | Mantero M |
collection | DOAJ |
description | Marco Mantero,1,2 Paola Rogliani,3 Marta Di Pasquale,1,2 Eva Polverino,4 Ernesto Crisafulli,5 Monica Guerrero,6 Andrea Gramegna,1,2 Mario Cazzola,3 Francesco Blasi1,2 1Department of Pathophysiology and Transplantation, Università degli Studi di Milano, 2Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Milan, 3Respiratory Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 4Respiratory Disease Department, Servei de Pneumologia, Hospital Universitari Vall d’Hebron (HUVH), Institut de Recerca Vall d’Hebron (VHIR), Barcelona, Spain; 5Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy; 6Hospital d’Igualada, Consorci Socisanitari de l’Anoia, Barcelona, Spain Abstract: Acute exacerbations are a leading cause of worsening COPD in terms of lung ­function decline, quality of life, and survival. They also have a relevant economic burden on the health care system. Determining the risk factors for acute exacerbation and early relapse could be a crucial element for a better management of COPD patients. This review analyzes the current knowledge and underlines the main risk factors for recurrent acute exacerbations. Comprehensive evaluation of COPD patients during stable phase and exacerbation could contribute to prevent treatment failure and relapses. Keywords: infections, prevention, treatment, COPD, exacerbations |
first_indexed | 2024-04-12T19:20:28Z |
format | Article |
id | doaj.art-641e88aa60004f77be8a12bafca65428 |
institution | Directory Open Access Journal |
issn | 1178-2005 |
language | English |
last_indexed | 2024-04-12T19:20:28Z |
publishDate | 2017-09-01 |
publisher | Dove Medical Press |
record_format | Article |
series | International Journal of COPD |
spelling | doaj.art-641e88aa60004f77be8a12bafca654282022-12-22T03:19:36ZengDove Medical PressInternational Journal of COPD1178-20052017-09-01Volume 122687269334640Acute exacerbations of COPD: risk factors for failure and relapseMantero MRogliani PDi Pasquale MPolverino ECrisafulli EGuerrero MGramegna ACazzola MBlasi FMarco Mantero,1,2 Paola Rogliani,3 Marta Di Pasquale,1,2 Eva Polverino,4 Ernesto Crisafulli,5 Monica Guerrero,6 Andrea Gramegna,1,2 Mario Cazzola,3 Francesco Blasi1,2 1Department of Pathophysiology and Transplantation, Università degli Studi di Milano, 2Internal Medicine Department, Respiratory Unit and Regional Adult Cystic Fibrosis Center, IRCCS Fondazione Cà Granda Ospedale Maggiore Policlinico, Milan, 3Respiratory Unit, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy; 4Respiratory Disease Department, Servei de Pneumologia, Hospital Universitari Vall d’Hebron (HUVH), Institut de Recerca Vall d’Hebron (VHIR), Barcelona, Spain; 5Department of Medicine and Surgery, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy; 6Hospital d’Igualada, Consorci Socisanitari de l’Anoia, Barcelona, Spain Abstract: Acute exacerbations are a leading cause of worsening COPD in terms of lung ­function decline, quality of life, and survival. They also have a relevant economic burden on the health care system. Determining the risk factors for acute exacerbation and early relapse could be a crucial element for a better management of COPD patients. This review analyzes the current knowledge and underlines the main risk factors for recurrent acute exacerbations. Comprehensive evaluation of COPD patients during stable phase and exacerbation could contribute to prevent treatment failure and relapses. Keywords: infections, prevention, treatment, COPD, exacerbations https://www.dovepress.com/acute-exacerbations-of-copd-risk-factors-for-failure-and-relapse-peer-reviewed-article-COPDInfectionspreventiontreatmentCOPDexacerbations |
spellingShingle | Mantero M Rogliani P Di Pasquale M Polverino E Crisafulli E Guerrero M Gramegna A Cazzola M Blasi F Acute exacerbations of COPD: risk factors for failure and relapse International Journal of COPD Infections prevention treatment COPD exacerbations |
title | Acute exacerbations of COPD: risk factors for failure and relapse |
title_full | Acute exacerbations of COPD: risk factors for failure and relapse |
title_fullStr | Acute exacerbations of COPD: risk factors for failure and relapse |
title_full_unstemmed | Acute exacerbations of COPD: risk factors for failure and relapse |
title_short | Acute exacerbations of COPD: risk factors for failure and relapse |
title_sort | acute exacerbations of copd risk factors for failure and relapse |
topic | Infections prevention treatment COPD exacerbations |
url | https://www.dovepress.com/acute-exacerbations-of-copd-risk-factors-for-failure-and-relapse-peer-reviewed-article-COPD |
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