Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter?
This study aims to evaluate changes in quality of life of cancer patients at the beginning of the first and the second cycle of chemotherapy (CT) in hospitals in Belo Horizonte, Minas Gerais State, Brazil. Longitudinal, prospective, descriptive study with a quantitative approach. We enrolled 230 pat...
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| Format: | Article |
| Language: | English |
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Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz
2021-09-01
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| Series: | Cadernos de Saúde Pública |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2021000805014&tlng=en |
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| author | Daniela Pena Moreira Giovana Paula Rezende Simino Ilka Afonso Reis Marcos Antonio da Cunha Santos Mariangela Leal Cherchiglia |
| author_facet | Daniela Pena Moreira Giovana Paula Rezende Simino Ilka Afonso Reis Marcos Antonio da Cunha Santos Mariangela Leal Cherchiglia |
| author_sort | Daniela Pena Moreira |
| collection | DOAJ |
| description | This study aims to evaluate changes in quality of life of cancer patients at the beginning of the first and the second cycle of chemotherapy (CT) in hospitals in Belo Horizonte, Minas Gerais State, Brazil. Longitudinal, prospective, descriptive study with a quantitative approach. We enrolled 230 patients, from a broader cohort, diagnosed with the five most frequent types of cancer (breast, colorectal, cervical, lung, and head and neck), aged 18 years or older, who were initiating CT for the first time. quality of life was assessed with the EORTC QLQ-C30 version 3, applied at the beginning of the first and second chemotherapy cycle. The paired Wilcoxon test was used to identify differences in quality of life between the two time points. A multivariate linear regression analysis was performed using the bootstrap method to investigate potential predictors of global health Status/quality of life. There was a significant increase in patients’ emotional function scores (p < 0.001) as well as symptom scores for pain (p = 0.026), diarrhea (p = 0.018), and nausea/vomiting (p < 0.001) after initiation of CT. Widowhood was associated with improvements in the global health Status/quality of life (p = 0.028), whereas the presence of cervical cancer (p = 0.034) and being underweight (p = 0.033) were related to poorer global health status/quality of life scores. CT has detrimental effects on patients’ physical health but, on the other hand, it leads to improvements in the emotional domain. Patients’ individual characteristics at the beginning of CT are associated with changes in their quality of life. Our study could help identify these characteristics. |
| first_indexed | 2024-04-11T17:26:47Z |
| format | Article |
| id | doaj.art-641f563badb0452ba86bb86a92bab1b8 |
| institution | Directory Open Access Journal |
| issn | 1678-4464 |
| language | English |
| last_indexed | 2024-04-11T17:26:47Z |
| publishDate | 2021-09-01 |
| publisher | Escola Nacional de Saúde Pública, Fundação Oswaldo Cruz |
| record_format | Article |
| series | Cadernos de Saúde Pública |
| spelling | doaj.art-641f563badb0452ba86bb86a92bab1b82022-12-22T04:12:16ZengEscola Nacional de Saúde Pública, Fundação Oswaldo CruzCadernos de Saúde Pública1678-44642021-09-0137810.1590/0102-311x00002220Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter?Daniela Pena Moreirahttps://orcid.org/0000-0002-3109-1342Giovana Paula Rezende Siminohttps://orcid.org/0000-0002-9814-3004Ilka Afonso Reishttps://orcid.org/0000-0001-7199-8590Marcos Antonio da Cunha Santoshttps://orcid.org/0000-0002-5228-8822Mariangela Leal Cherchigliahttps://orcid.org/0000-0001-5622-567XThis study aims to evaluate changes in quality of life of cancer patients at the beginning of the first and the second cycle of chemotherapy (CT) in hospitals in Belo Horizonte, Minas Gerais State, Brazil. Longitudinal, prospective, descriptive study with a quantitative approach. We enrolled 230 patients, from a broader cohort, diagnosed with the five most frequent types of cancer (breast, colorectal, cervical, lung, and head and neck), aged 18 years or older, who were initiating CT for the first time. quality of life was assessed with the EORTC QLQ-C30 version 3, applied at the beginning of the first and second chemotherapy cycle. The paired Wilcoxon test was used to identify differences in quality of life between the two time points. A multivariate linear regression analysis was performed using the bootstrap method to investigate potential predictors of global health Status/quality of life. There was a significant increase in patients’ emotional function scores (p < 0.001) as well as symptom scores for pain (p = 0.026), diarrhea (p = 0.018), and nausea/vomiting (p < 0.001) after initiation of CT. Widowhood was associated with improvements in the global health Status/quality of life (p = 0.028), whereas the presence of cervical cancer (p = 0.034) and being underweight (p = 0.033) were related to poorer global health status/quality of life scores. CT has detrimental effects on patients’ physical health but, on the other hand, it leads to improvements in the emotional domain. Patients’ individual characteristics at the beginning of CT are associated with changes in their quality of life. Our study could help identify these characteristics.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2021000805014&tlng=enNeoplasmsQuality of LifeDrug TherapyHealth ProfileCytotoxins |
| spellingShingle | Daniela Pena Moreira Giovana Paula Rezende Simino Ilka Afonso Reis Marcos Antonio da Cunha Santos Mariangela Leal Cherchiglia Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? Cadernos de Saúde Pública Neoplasms Quality of Life Drug Therapy Health Profile Cytotoxins |
| title | Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? |
| title_full | Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? |
| title_fullStr | Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? |
| title_full_unstemmed | Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? |
| title_short | Quality of life of patients with cancer undergoing chemotherapy in hospitals in Belo Horizonte, Minas Gerais State, Brazil: does individual characteristics matter? |
| title_sort | quality of life of patients with cancer undergoing chemotherapy in hospitals in belo horizonte minas gerais state brazil does individual characteristics matter |
| topic | Neoplasms Quality of Life Drug Therapy Health Profile Cytotoxins |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2021000805014&tlng=en |
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