Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy
Recently, rare diseases have received attention due to the need for improvement in diagnosed patients’ and their families’ lives. Duchenne muscular dystrophy (DMD) is a rare, severe, progressive, muscle-wasting disease. Today, the therapeutic standard for treating DMD is corticosteroids, which cause...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-10-01
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| Series: | Materials |
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| Online Access: | https://www.mdpi.com/1996-1944/16/19/6537 |
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| author | Greta Kaspute Bharani Dharan Arunagiri Rakshana Alexander Arunas Ramanavicius Urte Samukaite-Bubniene |
| author_facet | Greta Kaspute Bharani Dharan Arunagiri Rakshana Alexander Arunas Ramanavicius Urte Samukaite-Bubniene |
| author_sort | Greta Kaspute |
| collection | DOAJ |
| description | Recently, rare diseases have received attention due to the need for improvement in diagnosed patients’ and their families’ lives. Duchenne muscular dystrophy (DMD) is a rare, severe, progressive, muscle-wasting disease. Today, the therapeutic standard for treating DMD is corticosteroids, which cause serious adverse side effects. Nutraceuticals, e.g., herbal extracts or essential oils (EOs), are possible active substances to develop new drug delivery systems to improve DMD patients’ lives. New drug delivery systems lead to new drug effects, improved safety and accuracy, and new therapies for rare diseases. Herbal extracts and EOs combined with click chemistry can lead to the development of safer treatments for DMD. In this review, we focus on the need for novel drug delivery systems using EOs as the therapy for DMD and the potential use of click chemistry for drug delivery systems. New EO complex drug delivery systems may offer a new approach for improving muscle conditions and mental health issues associated with DMD. However, further research should identify the potential of these systems in the context of DMD. In this review, we discuss possibilities for applying EOs to DMD before implementing expensive research in a theoretical way. |
| first_indexed | 2024-03-10T21:40:45Z |
| format | Article |
| id | doaj.art-6420dac8f9d54c7ba7635b9fcf202c0b |
| institution | Directory Open Access Journal |
| issn | 1996-1944 |
| language | English |
| last_indexed | 2024-03-10T21:40:45Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Materials |
| spelling | doaj.art-6420dac8f9d54c7ba7635b9fcf202c0b2023-11-19T14:41:15ZengMDPI AGMaterials1996-19442023-10-011619653710.3390/ma16196537Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular DystrophyGreta Kaspute0Bharani Dharan Arunagiri1Rakshana Alexander2Arunas Ramanavicius3Urte Samukaite-Bubniene4Department of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Sauletekis av. 3, LT-10257 Vilnius, LithuaniaDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, LithuaniaDepartment of Physical Chemistry, Institute of Chemistry, Faculty of Chemistry and Geosciences, Vilnius University, Naugarduko Str. 24, LT-03225 Vilnius, LithuaniaDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Sauletekis av. 3, LT-10257 Vilnius, LithuaniaDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Sauletekis av. 3, LT-10257 Vilnius, LithuaniaRecently, rare diseases have received attention due to the need for improvement in diagnosed patients’ and their families’ lives. Duchenne muscular dystrophy (DMD) is a rare, severe, progressive, muscle-wasting disease. Today, the therapeutic standard for treating DMD is corticosteroids, which cause serious adverse side effects. Nutraceuticals, e.g., herbal extracts or essential oils (EOs), are possible active substances to develop new drug delivery systems to improve DMD patients’ lives. New drug delivery systems lead to new drug effects, improved safety and accuracy, and new therapies for rare diseases. Herbal extracts and EOs combined with click chemistry can lead to the development of safer treatments for DMD. In this review, we focus on the need for novel drug delivery systems using EOs as the therapy for DMD and the potential use of click chemistry for drug delivery systems. New EO complex drug delivery systems may offer a new approach for improving muscle conditions and mental health issues associated with DMD. However, further research should identify the potential of these systems in the context of DMD. In this review, we discuss possibilities for applying EOs to DMD before implementing expensive research in a theoretical way.https://www.mdpi.com/1996-1944/16/19/6537essential oilclick chemistrytargeted drug delivery systemDuchenne muscular dystrophyphytotherapymuscle-wasting disease |
| spellingShingle | Greta Kaspute Bharani Dharan Arunagiri Rakshana Alexander Arunas Ramanavicius Urte Samukaite-Bubniene Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy Materials essential oil click chemistry targeted drug delivery system Duchenne muscular dystrophy phytotherapy muscle-wasting disease |
| title | Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy |
| title_full | Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy |
| title_fullStr | Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy |
| title_full_unstemmed | Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy |
| title_short | Development of Essential Oil Delivery Systems by ‘Click Chemistry’ Methods: Possible Ways to Manage Duchenne Muscular Dystrophy |
| title_sort | development of essential oil delivery systems by click chemistry methods possible ways to manage duchenne muscular dystrophy |
| topic | essential oil click chemistry targeted drug delivery system Duchenne muscular dystrophy phytotherapy muscle-wasting disease |
| url | https://www.mdpi.com/1996-1944/16/19/6537 |
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