Method development, validation, and impurity measurement of β-estradiol from radiolabeled [131I]β-estradiol using radio-high-performance liquid chromatography for radioligand of saturation binding assay

Method development, validation, and impurity measurement of β-estradiol from radiolabeled [131I]β-estradiol using radio-high-performance liquid chromatography for radioligand of saturation binding assay

β-estradiol is an estrogen steroid hormone and acts as an estrogen receptor agonist. Radiolabeled β-estradiol is widely used as a radioligand for binding assays. In this present study, the synthesis of [131I]β-estradiol has been successfully carried out. Accordingly, the measurement of the radiochem...

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Bibliographic Details
Main Authors:	Isti Daruwati, Abednego Kristande Gwiharto, Hendris Wongso, Tri Hanggono Achmad, Mukh Syaifudin, Muchtaridi Muchtaridi
Format:	Article
Language:	English
Published:	Wolters Kluwer Medknow Publications 2023-01-01
Series:	Journal of Advanced Pharmaceutical Technology & Research
Subjects:	high-performance liquid chromatography radio-analytical method method validation radiochemical purity radioiodination β-estradiol
Online Access:	http://www.japtr.org/article.asp?issn=2231-4040;year=2023;volume=14;issue=2;spage=105;epage=112;aulast=Daruwati

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