Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction
Bismuth nitrate catalyzed efficient Hantzsch reaction via four-component coupling reactions of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione (dimedone), ethyl acetoacetate and ammonium acetate at 80 °C temperature was described as the preparation of 1,4-dihydropyridine derivatives. 2-Amino-4...
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| Format: | Article |
| Language: | English |
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Elsevier
2016-09-01
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| Series: | Journal of Saudi Chemical Society |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1319610312001433 |
| _version_ | 1818507443306496000 |
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| author | S. Sheik Mansoor K. Aswin K. Logaiya S.P.N. Sudhan |
| author_facet | S. Sheik Mansoor K. Aswin K. Logaiya S.P.N. Sudhan |
| author_sort | S. Sheik Mansoor |
| collection | DOAJ |
| description | Bismuth nitrate catalyzed efficient Hantzsch reaction via four-component coupling reactions of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione (dimedone), ethyl acetoacetate and ammonium acetate at 80 °C temperature was described as the preparation of 1,4-dihydropyridine derivatives. 2-Amino-4-phenyl-3-cyano-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives are also prepared under the same experimental conditions using aldehydes, dimedone, malononitrile and ammonium acetate in good yield. The higher catalytic activity of Bi(NO3)·5H2O is ascribed to its high acidity, thermal stability and water tolerance. The process presented here is operationally simple, environmentally benign and has excellent yield. Furthermore, the catalyst can be recovered conveniently and reused efficiently. |
| first_indexed | 2024-12-10T22:18:27Z |
| format | Article |
| id | doaj.art-642a79d24d7549a187bfabc437bb73f6 |
| institution | Directory Open Access Journal |
| issn | 1319-6103 |
| language | English |
| last_indexed | 2024-12-10T22:18:27Z |
| publishDate | 2016-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Saudi Chemical Society |
| spelling | doaj.art-642a79d24d7549a187bfabc437bb73f62022-12-22T01:31:24ZengElsevierJournal of Saudi Chemical Society1319-61032016-09-0120S1S100S10810.1016/j.jscs.2012.09.010Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reactionS. Sheik MansoorK. AswinK. LogaiyaS.P.N. SudhanBismuth nitrate catalyzed efficient Hantzsch reaction via four-component coupling reactions of aromatic aldehydes, 5,5-dimethyl-1,3-cyclohexanedione (dimedone), ethyl acetoacetate and ammonium acetate at 80 °C temperature was described as the preparation of 1,4-dihydropyridine derivatives. 2-Amino-4-phenyl-3-cyano-7,7-dimethyl-5-oxo-1,4,5,6,7,8-hexahydroquinoline derivatives are also prepared under the same experimental conditions using aldehydes, dimedone, malononitrile and ammonium acetate in good yield. The higher catalytic activity of Bi(NO3)·5H2O is ascribed to its high acidity, thermal stability and water tolerance. The process presented here is operationally simple, environmentally benign and has excellent yield. Furthermore, the catalyst can be recovered conveniently and reused efficiently.http://www.sciencedirect.com/science/article/pii/S1319610312001433Bismuth nitrate1,4-DihydropyridineHantzsch reactionOne-pot synthesisMulti component reaction |
| spellingShingle | S. Sheik Mansoor K. Aswin K. Logaiya S.P.N. Sudhan Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction Journal of Saudi Chemical Society Bismuth nitrate 1,4-Dihydropyridine Hantzsch reaction One-pot synthesis Multi component reaction |
| title | Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction |
| title_full | Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction |
| title_fullStr | Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction |
| title_full_unstemmed | Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction |
| title_short | Bismuth nitrate as an efficient recyclable catalyst for the one-pot multi component synthesis of 1,4-dihydropyridine derivatives through unsymmetrical Hantzsch reaction |
| title_sort | bismuth nitrate as an efficient recyclable catalyst for the one pot multi component synthesis of 1 4 dihydropyridine derivatives through unsymmetrical hantzsch reaction |
| topic | Bismuth nitrate 1,4-Dihydropyridine Hantzsch reaction One-pot synthesis Multi component reaction |
| url | http://www.sciencedirect.com/science/article/pii/S1319610312001433 |
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