Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005.
Between 2003 and 2005, highly pathogenic avian influenza A (H5N1) viruses caused large scale outbreaks in poultry in the Ho Chi Minh City area in Vietnam. We studied the prevalence of antibodies against H5N1 in poultry workers and cullers who were active in the program in Ho Chi Minh City in 2004 an...
| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2009-11-01
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| Series: | PLoS ONE |
| Online Access: | http://europepmc.org/articles/PMC2776305?pdf=render |
| _version_ | 1818258998735929344 |
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| author | Constance Schultsz Van Dung Nguyen Le Thanh Hai Quang Ha Do J S Malik Peiris Wilina Lim Jean-Michel Garcia Dac Tho Nguyen Thi Hoang Lan Nguyen Huu Tho Huynh Xuan Thao Phan H Rogier van Doorn Van Vinh Chau Nguyen Jeremy Farrar Menno D de Jong |
| author_facet | Constance Schultsz Van Dung Nguyen Le Thanh Hai Quang Ha Do J S Malik Peiris Wilina Lim Jean-Michel Garcia Dac Tho Nguyen Thi Hoang Lan Nguyen Huu Tho Huynh Xuan Thao Phan H Rogier van Doorn Van Vinh Chau Nguyen Jeremy Farrar Menno D de Jong |
| author_sort | Constance Schultsz |
| collection | DOAJ |
| description | Between 2003 and 2005, highly pathogenic avian influenza A (H5N1) viruses caused large scale outbreaks in poultry in the Ho Chi Minh City area in Vietnam. We studied the prevalence of antibodies against H5N1 in poultry workers and cullers who were active in the program in Ho Chi Minh City in 2004 and 2005.Single sera from 500 poultry workers and poultry cullers exposed to infected birds were tested for antibodies to avian influenza H5N1, using microneutralization assays and hemagglutination inhibition assay with horse blood. All sera tested negative using microneutralization tests. Three samples showed a 1ratio80 titer in the hemagglutination inhibition assay.This study provides additional support for the low transmissibility of clade 1 H5N1 to humans, but limited transmission to highly exposed persons cannot be excluded given the presence of low antibody titers in some individuals. |
| first_indexed | 2024-12-12T18:08:27Z |
| format | Article |
| id | doaj.art-642d659ccc0641dd90f7e5e8f9c90e3f |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-12-12T18:08:27Z |
| publishDate | 2009-11-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-642d659ccc0641dd90f7e5e8f9c90e3f2022-12-22T00:16:26ZengPublic Library of Science (PLoS)PLoS ONE1932-62032009-11-01411e794810.1371/journal.pone.0007948Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005.Constance SchultszVan Dung NguyenLe Thanh HaiQuang Ha DoJ S Malik PeirisWilina LimJean-Michel GarciaDac Tho NguyenThi Hoang Lan NguyenHuu Tho HuynhXuan Thao PhanH Rogier van DoornVan Vinh Chau NguyenJeremy FarrarMenno D de JongBetween 2003 and 2005, highly pathogenic avian influenza A (H5N1) viruses caused large scale outbreaks in poultry in the Ho Chi Minh City area in Vietnam. We studied the prevalence of antibodies against H5N1 in poultry workers and cullers who were active in the program in Ho Chi Minh City in 2004 and 2005.Single sera from 500 poultry workers and poultry cullers exposed to infected birds were tested for antibodies to avian influenza H5N1, using microneutralization assays and hemagglutination inhibition assay with horse blood. All sera tested negative using microneutralization tests. Three samples showed a 1ratio80 titer in the hemagglutination inhibition assay.This study provides additional support for the low transmissibility of clade 1 H5N1 to humans, but limited transmission to highly exposed persons cannot be excluded given the presence of low antibody titers in some individuals.http://europepmc.org/articles/PMC2776305?pdf=render |
| spellingShingle | Constance Schultsz Van Dung Nguyen Le Thanh Hai Quang Ha Do J S Malik Peiris Wilina Lim Jean-Michel Garcia Dac Tho Nguyen Thi Hoang Lan Nguyen Huu Tho Huynh Xuan Thao Phan H Rogier van Doorn Van Vinh Chau Nguyen Jeremy Farrar Menno D de Jong Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. PLoS ONE |
| title | Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. |
| title_full | Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. |
| title_fullStr | Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. |
| title_full_unstemmed | Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. |
| title_short | Prevalence of antibodies against avian influenza A (H5N1) virus among Cullers and poultry workers in Ho Chi Minh City, 2005. |
| title_sort | prevalence of antibodies against avian influenza a h5n1 virus among cullers and poultry workers in ho chi minh city 2005 |
| url | http://europepmc.org/articles/PMC2776305?pdf=render |
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