A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR

A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR

<p>Abstract</p> <p>Background</p> <p>Isolation of novel retroviral restriction factors will open new avenues for anti-HIV/AIDS treatment. Although HIV-1 replication is restricted by APOBEC3G/APOBEC3F, TRIM5α, and CD317, none defend HIV-1 infection under natural conditio...

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Bibliographic Details
Main Authors: Zhou Tao, Han Yanxing, Dang Ying, Wang Xiaojun, Zheng Yong-Hui
Format: Article
Language:English
Published: BMC 2009-04-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/6/1/31

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