Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil
Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA a...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Fundação Oswaldo Cruz (FIOCRUZ)
2013-02-01
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| Series: | Memorias do Instituto Oswaldo Cruz |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100004&lng=en&tlng=en |
| _version_ | 1797712603812724736 |
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| author | Paulo Victor Pereira Baio Higor Franceschi Mota Andréa D'avila Freitas Débora Leandro Rama Gomes Juliana Nunes Ramos Lincoln Oliveira Sant'Anna Mônica Cristina Souza Thereza Cristina Ferreira Camello Raphael Hirata Junior Verônica Viana Vieira Ana Luíza Mattos-Guaraldi |
| author_facet | Paulo Victor Pereira Baio Higor Franceschi Mota Andréa D'avila Freitas Débora Leandro Rama Gomes Juliana Nunes Ramos Lincoln Oliveira Sant'Anna Mônica Cristina Souza Thereza Cristina Ferreira Camello Raphael Hirata Junior Verônica Viana Vieira Ana Luíza Mattos-Guaraldi |
| author_sort | Paulo Victor Pereira Baio |
| collection | DOAJ |
| description | Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases. |
| first_indexed | 2024-03-12T07:23:14Z |
| format | Article |
| id | doaj.art-642f60eababc4102b9c5c3ba51330820 |
| institution | Directory Open Access Journal |
| issn | 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T07:23:14Z |
| publishDate | 2013-02-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-642f60eababc4102b9c5c3ba513308202023-09-02T22:14:56ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz1678-80602013-02-011081232910.1590/S0074-02762013000100004S0074-02762013000100004Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, BrazilPaulo Victor Pereira Baio0Higor Franceschi Mota1Andréa D'avila Freitas2Débora Leandro Rama Gomes3Juliana Nunes Ramos4Lincoln Oliveira Sant'Anna5Mônica Cristina Souza6Thereza Cristina Ferreira Camello7Raphael Hirata Junior8Verônica Viana Vieira9Ana Luíza Mattos-Guaraldi10Universidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroUniversidade do Estado do Rio de JaneiroFundação Oswaldo CruzUniversidade do Estado do Rio de JaneiroCorynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100004&lng=en&tlng=enCorynebacterium striatumnosocomial outbreakPFGEmultidrug-resistant clones |
| spellingShingle | Paulo Victor Pereira Baio Higor Franceschi Mota Andréa D'avila Freitas Débora Leandro Rama Gomes Juliana Nunes Ramos Lincoln Oliveira Sant'Anna Mônica Cristina Souza Thereza Cristina Ferreira Camello Raphael Hirata Junior Verônica Viana Vieira Ana Luíza Mattos-Guaraldi Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil Memorias do Instituto Oswaldo Cruz Corynebacterium striatum nosocomial outbreak PFGE multidrug-resistant clones |
| title | Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil |
| title_full | Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil |
| title_fullStr | Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil |
| title_full_unstemmed | Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil |
| title_short | Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil |
| title_sort | clonal multidrug resistant corynebacterium striatum within a nosocomial environment rio de janeiro brazil |
| topic | Corynebacterium striatum nosocomial outbreak PFGE multidrug-resistant clones |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100004&lng=en&tlng=en |
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