Improving the flux distributions simulated with genome-scale metabolic models of Saccharomyces cerevisiae
Genome-scale metabolic models (GEMs) can be used to evaluate genotype-phenotype relationships and their application to microbial strain engineering is increasing in popularity. Some of the algorithms used to simulate the phenotypes of mutant strains require the determination of a wild-type flux dist...
Main Authors: | Rui Pereira, Jens Nielsen, Isabel Rocha |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016-12-01
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Series: | Metabolic Engineering Communications |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2214030116300141 |
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