Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products
Sea cucumbers are a class of marine invertebrates and a source of food and drug. Numerous microorganisms are associated with sea cucumbers. Seventy-eight genera of bacteria belonging to 47 families in four phyla, and 29 genera of fungi belonging to 24 families in the phylum Ascomycota have been cult...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-08-01
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| Series: | Marine Drugs |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1660-3397/19/8/461 |
| _version_ | 1797523134128062464 |
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| author | Lei Chen Xiao-Yu Wang Run-Ze Liu Guang-Yu Wang |
| author_facet | Lei Chen Xiao-Yu Wang Run-Ze Liu Guang-Yu Wang |
| author_sort | Lei Chen |
| collection | DOAJ |
| description | Sea cucumbers are a class of marine invertebrates and a source of food and drug. Numerous microorganisms are associated with sea cucumbers. Seventy-eight genera of bacteria belonging to 47 families in four phyla, and 29 genera of fungi belonging to 24 families in the phylum Ascomycota have been cultured from sea cucumbers. Sea-cucumber-associated microorganisms produce diverse secondary metabolites with various biological activities, including cytotoxic, antimicrobial, enzyme-inhibiting, and antiangiogenic activities. In this review, we present the current list of the 145 natural products from microorganisms associated with sea cucumbers, which include primarily polyketides, as well as alkaloids and terpenoids. These results indicate the potential of the microorganisms associated with sea cucumbers as sources of bioactive natural products. |
| first_indexed | 2024-03-10T08:39:04Z |
| format | Article |
| id | doaj.art-643679aa7de048369904fd208ce908b5 |
| institution | Directory Open Access Journal |
| issn | 1660-3397 |
| language | English |
| last_indexed | 2024-03-10T08:39:04Z |
| publishDate | 2021-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Marine Drugs |
| spelling | doaj.art-643679aa7de048369904fd208ce908b52023-11-22T08:26:03ZengMDPI AGMarine Drugs1660-33972021-08-0119846110.3390/md19080461Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural ProductsLei Chen0Xiao-Yu Wang1Run-Ze Liu2Guang-Yu Wang3Department of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai 264209, ChinaDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai 264209, ChinaDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai 264209, ChinaDepartment of Bioengineering, School of Marine Science and Technology, Harbin Institute of Technology at Weihai, Weihai 264209, ChinaSea cucumbers are a class of marine invertebrates and a source of food and drug. Numerous microorganisms are associated with sea cucumbers. Seventy-eight genera of bacteria belonging to 47 families in four phyla, and 29 genera of fungi belonging to 24 families in the phylum Ascomycota have been cultured from sea cucumbers. Sea-cucumber-associated microorganisms produce diverse secondary metabolites with various biological activities, including cytotoxic, antimicrobial, enzyme-inhibiting, and antiangiogenic activities. In this review, we present the current list of the 145 natural products from microorganisms associated with sea cucumbers, which include primarily polyketides, as well as alkaloids and terpenoids. These results indicate the potential of the microorganisms associated with sea cucumbers as sources of bioactive natural products.https://www.mdpi.com/1660-3397/19/8/461sea cucumberbioactivitydiversitymicroorganismpolyketidesalkaloids |
| spellingShingle | Lei Chen Xiao-Yu Wang Run-Ze Liu Guang-Yu Wang Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products Marine Drugs sea cucumber bioactivity diversity microorganism polyketides alkaloids |
| title | Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products |
| title_full | Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products |
| title_fullStr | Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products |
| title_full_unstemmed | Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products |
| title_short | Culturable Microorganisms Associated with Sea Cucumbers and Microbial Natural Products |
| title_sort | culturable microorganisms associated with sea cucumbers and microbial natural products |
| topic | sea cucumber bioactivity diversity microorganism polyketides alkaloids |
| url | https://www.mdpi.com/1660-3397/19/8/461 |
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