A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy
Coronavirus 19 (COVID-19) is well known for causing acute respiratory distress syndrome. Among other systemic complications, myocarditis is a frequently reported presentation as well as complication. One systematic review reported a 14% mortality rate in patients with COVID-19 myocarditis. Endomyoca...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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SMC MEDIA SRL
2023-08-01
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| Series: | European Journal of Case Reports in Internal Medicine |
| Subjects: | |
| Online Access: | https://www.ejcrim.com/index.php/EJCRIM/article/view/3877 |
| _version_ | 1797692462887600128 |
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| author | Su Khine Srujan Edupuganti Ghassan Bachuwa |
| author_facet | Su Khine Srujan Edupuganti Ghassan Bachuwa |
| author_sort | Su Khine |
| collection | DOAJ |
| description | Coronavirus 19 (COVID-19) is well known for causing acute respiratory distress syndrome. Among other systemic complications, myocarditis is a frequently reported presentation as well as complication. One systematic review reported a 14% mortality rate in patients with COVID-19 myocarditis. Endomyocardial biopsy is a definitive diagnostic test but has been a challenge to perform in most cases of COVID myocarditis due to the contagious nature of the disease. Patients presenting with new cardiomyopathy with troponin leak and arrhythmias, supported by recent COVID-19 diagnosis should be suspected for COVID-induced myocarditis. Supportive treatment has been the mainstay of treatment with limited data on immunotherapy and colchicine. Our case is about a male in his 50s who had a cardiac arrest due to ventricular fibrillations, with a positive COVID-19 test. Further workup showed severe non-ischaemic cardiomyopathy with an EF of 15–20%. He was treated with intravenous immunotherapy and colchicine. A repeat echocardiogram 3 days later showed resolution of cardiomyopathy. Our case report highlights the possible beneficial effects of immunotherapy and colchicine in viral myocarditis. |
| first_indexed | 2024-03-12T02:28:56Z |
| format | Article |
| id | doaj.art-6437adbbd01444b59206f7810deb508d |
| institution | Directory Open Access Journal |
| issn | 2284-2594 |
| language | English |
| last_indexed | 2024-03-12T02:28:56Z |
| publishDate | 2023-08-01 |
| publisher | SMC MEDIA SRL |
| record_format | Article |
| series | European Journal of Case Reports in Internal Medicine |
| spelling | doaj.art-6437adbbd01444b59206f7810deb508d2023-09-05T09:56:45ZengSMC MEDIA SRLEuropean Journal of Case Reports in Internal Medicine2284-25942023-08-0110.12890/2023_0038773412A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapySu Khine0Srujan Edupuganti1Ghassan Bachuwa2Department of Internal Medicine, Hurley Medical Center, Flint, Michigan, USADepartment of Internal Medicine-Pediatrics, Hurley Medical Center, Flint, Michigan, USADepartment of Internal Medicine, Hurley Medical Center, Flint, Michigan, USACoronavirus 19 (COVID-19) is well known for causing acute respiratory distress syndrome. Among other systemic complications, myocarditis is a frequently reported presentation as well as complication. One systematic review reported a 14% mortality rate in patients with COVID-19 myocarditis. Endomyocardial biopsy is a definitive diagnostic test but has been a challenge to perform in most cases of COVID myocarditis due to the contagious nature of the disease. Patients presenting with new cardiomyopathy with troponin leak and arrhythmias, supported by recent COVID-19 diagnosis should be suspected for COVID-induced myocarditis. Supportive treatment has been the mainstay of treatment with limited data on immunotherapy and colchicine. Our case is about a male in his 50s who had a cardiac arrest due to ventricular fibrillations, with a positive COVID-19 test. Further workup showed severe non-ischaemic cardiomyopathy with an EF of 15–20%. He was treated with intravenous immunotherapy and colchicine. A repeat echocardiogram 3 days later showed resolution of cardiomyopathy. Our case report highlights the possible beneficial effects of immunotherapy and colchicine in viral myocarditis.https://www.ejcrim.com/index.php/EJCRIM/article/view/3877covid-19 myocarditisnon-ischemic cardiomyopathyventricular tachycardiacolchicineimmunotherapy |
| spellingShingle | Su Khine Srujan Edupuganti Ghassan Bachuwa A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy European Journal of Case Reports in Internal Medicine covid-19 myocarditis non-ischemic cardiomyopathy ventricular tachycardia colchicine immunotherapy |
| title | A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy |
| title_full | A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy |
| title_fullStr | A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy |
| title_full_unstemmed | A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy |
| title_short | A case of severe cardiomyopathy due to COVID-induced myocarditis, completely resolved after colchicine and immunoglobulin therapy |
| title_sort | case of severe cardiomyopathy due to covid induced myocarditis completely resolved after colchicine and immunoglobulin therapy |
| topic | covid-19 myocarditis non-ischemic cardiomyopathy ventricular tachycardia colchicine immunotherapy |
| url | https://www.ejcrim.com/index.php/EJCRIM/article/view/3877 |
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