An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation

Spur cell anemia is acquired hemolytic anemia seen in patients with advanced liver disease, particularly in the setting of alcoholism, and warrants urgent liver transplant evaluation. We describe the case of a 58-year-old female with alcoholic cirrhosis who presented with worsening liver disease, p...

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Main Authors: Vatsala Katiyar, Apaar Dadlani, Ishaan Vohra, Kamila Cisak, Ashutosh Barve
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2022-04-01
Series:International Journal of Hematology-Oncology and Stem Cell Research
Subjects:
Online Access:https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1662
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author Vatsala Katiyar
Apaar Dadlani
Ishaan Vohra
Kamila Cisak
Ashutosh Barve
author_facet Vatsala Katiyar
Apaar Dadlani
Ishaan Vohra
Kamila Cisak
Ashutosh Barve
author_sort Vatsala Katiyar
collection DOAJ
description Spur cell anemia is acquired hemolytic anemia seen in patients with advanced liver disease, particularly in the setting of alcoholism, and warrants urgent liver transplant evaluation. We describe the case of a 58-year-old female with alcoholic cirrhosis who presented with worsening liver disease, profound anemia poorly responsive to blood transfusions, and multiple spur cells on the peripheral smear. She underwent a liver transplant, which led to the resolution of hematologic abnormalities and the need for transfusions. Our case highlights the significance of spur cell anemia as a harbinger of poor prognosis in patients with advanced liver disease and its reversibility with liver transplantation
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series International Journal of Hematology-Oncology and Stem Cell Research
spelling doaj.art-6439c294d8604d9f8471d3c76197fb7c2023-09-03T00:38:57ZengTehran University of Medical SciencesInternational Journal of Hematology-Oncology and Stem Cell Research2008-22072022-04-01162An Unusual Case of Hemolytic Anemia Reversed with Liver TransplantationVatsala Katiyar0Apaar Dadlani1Ishaan Vohra2Kamila Cisak3Ashutosh Barve4Division of Medical Oncology and Hematology, Department of Internal Medicine, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KYDepartment of Internal Medicine, University of Louisville School of Medicine, Louisville, USADivision of Gastroenterology, Hepatology and Nutrition, University of Illinois College of Medicine Peoria, Peoria, USADivision of Medical Oncology and Hematology, Department of Internal Medicine, James Graham Brown Cancer Center, University of Louisville School of Medicine, Louisville, KYDivision of Gastroenterology, Hepatology and Nutrition, University of Louisville School of Medicine, Louisville, USA Spur cell anemia is acquired hemolytic anemia seen in patients with advanced liver disease, particularly in the setting of alcoholism, and warrants urgent liver transplant evaluation. We describe the case of a 58-year-old female with alcoholic cirrhosis who presented with worsening liver disease, profound anemia poorly responsive to blood transfusions, and multiple spur cells on the peripheral smear. She underwent a liver transplant, which led to the resolution of hematologic abnormalities and the need for transfusions. Our case highlights the significance of spur cell anemia as a harbinger of poor prognosis in patients with advanced liver disease and its reversibility with liver transplantation https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1662Spur cell anemia; Alcoholic cirrhosis; Liver transplant; Zieve's disease; Plasmapheresis
spellingShingle Vatsala Katiyar
Apaar Dadlani
Ishaan Vohra
Kamila Cisak
Ashutosh Barve
An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
International Journal of Hematology-Oncology and Stem Cell Research
Spur cell anemia; Alcoholic cirrhosis; Liver transplant; Zieve's disease; Plasmapheresis
title An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
title_full An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
title_fullStr An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
title_full_unstemmed An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
title_short An Unusual Case of Hemolytic Anemia Reversed with Liver Transplantation
title_sort unusual case of hemolytic anemia reversed with liver transplantation
topic Spur cell anemia; Alcoholic cirrhosis; Liver transplant; Zieve's disease; Plasmapheresis
url https://ijhoscr.tums.ac.ir/index.php/ijhoscr/article/view/1662
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