Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life

In situ generated lesion of red blood cells decreases the quality of stored blood and limits its shelf-life. Here, the authors demonstrate that intermittent scavenging of storage lesions using electrostatic interactions by nanofibrous sheets could enhance the quality and shelf-life of stored blood.

Bibliographic Details
Main Authors: Subhashini Pandey, Manohar Mahato, Preethem Srinath, Utkarsh Bhutani, Tanu Jain Goap, Priusha Ravipati, Praveen Kumar Vemula
Format: Article
Language:English
Published: Nature Portfolio 2022-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35269-3
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author Subhashini Pandey
Manohar Mahato
Preethem Srinath
Utkarsh Bhutani
Tanu Jain Goap
Priusha Ravipati
Praveen Kumar Vemula
author_facet Subhashini Pandey
Manohar Mahato
Preethem Srinath
Utkarsh Bhutani
Tanu Jain Goap
Priusha Ravipati
Praveen Kumar Vemula
author_sort Subhashini Pandey
collection DOAJ
description In situ generated lesion of red blood cells decreases the quality of stored blood and limits its shelf-life. Here, the authors demonstrate that intermittent scavenging of storage lesions using electrostatic interactions by nanofibrous sheets could enhance the quality and shelf-life of stored blood.
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spelling doaj.art-643a2fe6d0ca4a3a925f65c06ef670372022-12-22T02:48:39ZengNature PortfolioNature Communications2041-17232022-12-0113111510.1038/s41467-022-35269-3Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-lifeSubhashini Pandey0Manohar Mahato1Preethem Srinath2Utkarsh Bhutani3Tanu Jain Goap4Priusha Ravipati5Praveen Kumar Vemula6Institute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostInstitute for Stem Cell Science and Regenerative Medicine (inStem), GKVK PostIn situ generated lesion of red blood cells decreases the quality of stored blood and limits its shelf-life. Here, the authors demonstrate that intermittent scavenging of storage lesions using electrostatic interactions by nanofibrous sheets could enhance the quality and shelf-life of stored blood.https://doi.org/10.1038/s41467-022-35269-3
spellingShingle Subhashini Pandey
Manohar Mahato
Preethem Srinath
Utkarsh Bhutani
Tanu Jain Goap
Priusha Ravipati
Praveen Kumar Vemula
Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
Nature Communications
title Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
title_full Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
title_fullStr Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
title_full_unstemmed Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
title_short Intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf-life
title_sort intermittent scavenging of storage lesion from stored red blood cells by electrospun nanofibrous sheets enhances their quality and shelf life
url https://doi.org/10.1038/s41467-022-35269-3
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