The Pathogenesis of Ischemia-Reperfusion Induced Acute Kidney Injury Depends on Renal Neutrophil Recruitment Whereas Sepsis-Induced AKI Does Not

The Pathogenesis of Ischemia-Reperfusion Induced Acute Kidney Injury Depends on Renal Neutrophil Recruitment Whereas Sepsis-Induced AKI Does Not

Acute kidney injury (AKI) may be induced by different causes, including renal ischemia-reperfusion injury and sepsis, which represent the most common reasons for AKI in hospitalized patients. AKI is defined by reduced urine production and/or increased plasma creatinine. However, this definition does...

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Bibliographic Details
Main Authors: Zhenhan Li, Nadine Ludwig, Katharina Thomas, Sina Mersmann, Martin Lehmann, Dietmar Vestweber, Jean-Francois Pittet, Hernando Gomez, John A. Kellum, Jan Rossaint, Alexander Zarbock
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
neutrophils
kidney
ischemia-reperfusion injury
cecal ligation and puncture
sepsis
acute kidney injury
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.843782/full

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