Aromatic L-amino acid decarboxylase (AADC) is crucial for brain development and motor functions.

Aromatic L-amino acid decarboxylase (AADC) is crucial for brain development and motor functions.

Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare pediatric neuro-metabolic disease in children. Due to the lack of an animal model, its pathogenetic mechanism is poorly understood. To study the role of AADC in brain development, a zebrafish model of AADC deficiency was generated. We i...

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Bibliographic Details
Main Authors: De-Fen Shih, Chung-Der Hsiao, Ming-Yuan Min, Wen-Sung Lai, Chianne-Wen Yang, Wang-Tso Lee, Shyh-Jye Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3734303?pdf=render

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