Mosaic patterns of selection in genomic regions associated with diverse human traits.

Natural selection shapes the genetic architecture of many human traits. However, the prevalence of different modes of selection on genomic regions associated with variation in traits remains poorly understood. To address this, we developed an efficient computational framework to calculate positive a...

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Bibliographic Details
Main Authors: Abin Abraham, Abigail L LaBella, John A Capra, Antonis Rokas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1010494