IL-17 produced during Trypanosoma cruzi infection plays a central role in regulating parasite-induced myocarditis.
BACKGROUND: Chagas disease is a neglected disease caused by the intracellular parasite Trypanosoma cruzi. Around 30% of the infected patients develop chronic cardiomyopathy or megasyndromes, which are high-cost morbid conditions. Immune response against myocardial self-antigens and exacerbated Th1 c...
Main Authors: | Paulo Marcos da Matta Guedes, Fredy R S Gutierrez, Flavia L Maia, Cristiane M Milanezi, Grace K Silva, Wander R Pavanelli, João S Silva |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-01-01
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Series: | PLoS Neglected Tropical Diseases |
Online Access: | http://europepmc.org/articles/PMC2821906?pdf=render |
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