Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease
(1) Background: Betel nut chewing injures bodily health. Although, the relationship between betel nut chewing and kidney stone disease (KSD) is unknown. (2) Methods: We analyzed 43,636 men from Taiwan Biobank. We divided them into two groups on the status of betel nut chewing, the never-chewer and e...
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MDPI AG
2022-01-01
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| Series: | Journal of Personalized Medicine |
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| Online Access: | https://www.mdpi.com/2075-4426/12/2/126 |
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| author | Chun-Kai Chang Jia-In Lee Chu-Fen Chang Yung-Chin Lee Jhen-Hao Jhan Hsun-Shuan Wang Jung-Tsung Shen Yao-Hsuan Tsao Shu-Pin Huang Jiun-Hung Geng |
| author_facet | Chun-Kai Chang Jia-In Lee Chu-Fen Chang Yung-Chin Lee Jhen-Hao Jhan Hsun-Shuan Wang Jung-Tsung Shen Yao-Hsuan Tsao Shu-Pin Huang Jiun-Hung Geng |
| author_sort | Chun-Kai Chang |
| collection | DOAJ |
| description | (1) Background: Betel nut chewing injures bodily health. Although, the relationship between betel nut chewing and kidney stone disease (KSD) is unknown. (2) Methods: We analyzed 43,636 men from Taiwan Biobank. We divided them into two groups on the status of betel nut chewing, the never-chewer and ever-chewer groups. Self-reported diagnosed KSD was defined as the subject’s medical history of KSD in the questionnaire. Logistic regression was used to analyze the association of betel nut chewing and the risk of KSD. (3) Results: The mean age of subjects in the present study was 50 years, and 16% were ever-chewers. KSD was observed in 3759 (10.3%) and 894 (12.6%) participants in the group of never-chewer and ever-chewer groups, respectively. Higher risk of KSD was found in participants with betel nut chewing compared with to without betel nut chewing (odds ratio (OR), 1.094; 95% confidence interval (95% CI), 1.001 to 1.196). Furthermore, the daily amounts of betel nut chewing >30 quids was associated with a more than 1.5-fold increase (OR, 1.571; 95% CI, 1.186 to 2.079) in the odds of KSD; (4) Conclusions: Our study suggests that betel nut chewing is associated with the risk of KSD and warrants further attention to this problem. |
| first_indexed | 2024-03-09T21:38:11Z |
| format | Article |
| id | doaj.art-643f8ae281884e8bb302c0dbe1166fef |
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| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-09T21:38:11Z |
| publishDate | 2022-01-01 |
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| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-643f8ae281884e8bb302c0dbe1166fef2023-11-23T20:38:39ZengMDPI AGJournal of Personalized Medicine2075-44262022-01-0112212610.3390/jpm12020126Betel Nut Chewing Is Associated with the Risk of Kidney Stone DiseaseChun-Kai Chang0Jia-In Lee1Chu-Fen Chang2Yung-Chin Lee3Jhen-Hao Jhan4Hsun-Shuan Wang5Jung-Tsung Shen6Yao-Hsuan Tsao7Shu-Pin Huang8Jiun-Hung Geng9Department of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Psychiatry, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, TaiwanDepartment of Physical Therapy, Tzu Chi University, Hualien 97004, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, TaiwanDepartment of Urology, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung 80756, TaiwanDepartment of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung 812, Taiwan(1) Background: Betel nut chewing injures bodily health. Although, the relationship between betel nut chewing and kidney stone disease (KSD) is unknown. (2) Methods: We analyzed 43,636 men from Taiwan Biobank. We divided them into two groups on the status of betel nut chewing, the never-chewer and ever-chewer groups. Self-reported diagnosed KSD was defined as the subject’s medical history of KSD in the questionnaire. Logistic regression was used to analyze the association of betel nut chewing and the risk of KSD. (3) Results: The mean age of subjects in the present study was 50 years, and 16% were ever-chewers. KSD was observed in 3759 (10.3%) and 894 (12.6%) participants in the group of never-chewer and ever-chewer groups, respectively. Higher risk of KSD was found in participants with betel nut chewing compared with to without betel nut chewing (odds ratio (OR), 1.094; 95% confidence interval (95% CI), 1.001 to 1.196). Furthermore, the daily amounts of betel nut chewing >30 quids was associated with a more than 1.5-fold increase (OR, 1.571; 95% CI, 1.186 to 2.079) in the odds of KSD; (4) Conclusions: Our study suggests that betel nut chewing is associated with the risk of KSD and warrants further attention to this problem.https://www.mdpi.com/2075-4426/12/2/126epidemiologic studykidney stone diseasenephrolithiasisbetel nutareca nutrisk factors |
| spellingShingle | Chun-Kai Chang Jia-In Lee Chu-Fen Chang Yung-Chin Lee Jhen-Hao Jhan Hsun-Shuan Wang Jung-Tsung Shen Yao-Hsuan Tsao Shu-Pin Huang Jiun-Hung Geng Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease Journal of Personalized Medicine epidemiologic study kidney stone disease nephrolithiasis betel nut areca nut risk factors |
| title | Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease |
| title_full | Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease |
| title_fullStr | Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease |
| title_full_unstemmed | Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease |
| title_short | Betel Nut Chewing Is Associated with the Risk of Kidney Stone Disease |
| title_sort | betel nut chewing is associated with the risk of kidney stone disease |
| topic | epidemiologic study kidney stone disease nephrolithiasis betel nut areca nut risk factors |
| url | https://www.mdpi.com/2075-4426/12/2/126 |
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