Successful Proof-of-Concept for Topical Delivery of Novel Peptide ALM201 with Potential Usefulness for Treating Neovascular Eye Disorders

Successful Proof-of-Concept for Topical Delivery of Novel Peptide ALM201 with Potential Usefulness for Treating Neovascular Eye Disorders

Purpose: To evaluate the therapeutic benefit of a novel peptide, ALM201, in ocular pathologic vascularization. Design: Experimental study in mouse, rat, and rabbit animal models. Participants: Ten-week-old Lister Hooded male rats, 8-week-old Brown Norway male rats, 9-day-old C57BL/6J mice, and 12-mo...

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Bibliographic Details
Main Authors:	Gideon Obasanmi, PhD, M. Andrew Nesbit, PhD, Diego Cobice, PhD, Logan Mackay, PhD, Stuart McGimpsey, MBBCh, BAO, Mark Wappett, MRes, Aaron N. Cranston, PhD, Tara C.B. Moore, PhD
Format:	Article
Language:	English
Published:	Elsevier 2022-06-01
Series:	Ophthalmology Science
Subjects:	Age-related macular degeneration Angiogenesis Choroidal neovascularization Corneal vascularization Ocular neovascularization
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666914522000392

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