Defining the Relative Role of Insulin Clearance in Early Dysglycemia in Relation to Insulin Sensitivity and Insulin Secretion: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)

Defining the Relative Role of Insulin Clearance in Early Dysglycemia in Relation to Insulin Sensitivity and Insulin Secretion: The Microbiome and Insulin Longitudinal Evaluation Study (MILES)

Insulin resistance and insufficient insulin secretion are well-recognized contributors to type 2 diabetes. A potential role of reduced insulin clearance has been suggested, but few studies have investigated the contribution of insulin clearance while simultaneously examining decreased insulin sensit...

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Bibliographic Details
Main Authors: Alexis C. Wood, Elizabeth T. Jensen, Alain G. Bertoni, Gautam Ramesh, Stephen S. Rich, Jerome I. Rotter, Yii-Der I. Chen, Mark O. Goodarzi
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Metabolites
Subjects:
insulin sensitivity
insulin secretion
insulin clearance
disposition index
prediabetes
diabetes
Online Access:https://www.mdpi.com/2218-1989/11/7/420

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