Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-α and IL-17A Expression in Mucosal Inflammation

Intestinal Epithelium-Derived Luminally Released Extracellular Vesicles in Sepsis Exhibit the Ability to Suppress TNF-α and IL-17A Expression in Mucosal Inflammation

Sepsis is a systemic inflammatory disorder induced by a dysregulated immune response to infection resulting in dysfunction of multiple critical organs, including the intestines. Previous studies have reported contrasting results regarding the abilities of exosomes circulating in the blood of sepsis...

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Bibliographic Details
Main Authors: Michael G. Appiah, Eun Jeong Park, Samuel Darkwah, Eiji Kawamoto, Yuichi Akama, Arong Gaowa, Manisha Kalsan, Shandar Ahmad, Motomu Shimaoka
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:International Journal of Molecular Sciences
Subjects:
sepsis
intestinal epithelial cells
inflammation
extracellular vesicles
TNF-α
IL-17A
Online Access:https://www.mdpi.com/1422-0067/21/22/8445

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